144 0001535472 XXXXXXXX LIVE 0001110803 ILLUMINA, INC. 001-35406 5200 ILLUMINA WAY SAN DIEGO CA 92122 8582024500 Corvex Management LP Affiliate of Director (1) Common Stock, par value $0.01 per share Goldman Sachs & Co. LLC

200 West Street New York NY 10282

840000 166454400.00 151000000 08/04/2026 Nasdaq Global Select Common Stock, par value $0.01 per share 10/25/2023 Purchases of shares of Common Stock in the open market (2) Purchases from counterparties in open market transactions N 840000 10/25/2023 Cash N Corvex Management LP (1)

667 Madison Avenue New York NY 10065

Common Stock, par value $0.01 per share 05/13/2026 225067 32760165.38 Corvex Management LP (1)

667 Madison Avenue New York NY 10065

Common Stock, par value $0.01 per share 05/14/2026 104393 15172549.18 Corvex Management LP (1)

667 Madison Avenue New York NY 10065

Common Stock, par value $0.01 per share 05/28/2026 220000 34686783.32 Corvex Management LP (1)

667 Madison Avenue New York NY 10065

Common Stock, par value $0.01 per share 05/29/2026 214596 35088672.43 Corvex Management LP (1)

667 Madison Avenue New York NY 10065

Common Stock, par value $0.01 per share 06/01/2026 235000 38454606.87 1. Corvex Management LP (Corvex) may be deemed to be the beneficial owner of shares of Common Stock (Common Stock) of Illumina, Inc. (the Issuer) held by one or more funds for which Corvex serves as investment adviser. The general partner of Corvex is controlled by Keith Meister, who serves as a director on the Board of Directors of the Issuer. 2. Shares of Common Stock to be sold were purchased between October 25, 2023 and March 27, 2025 in various open market transactions. 08/04/2026 /s/ Patrick Dooley, authorized signatory of Corvex Management LP