144 0001993292 XXXXXXXX LIVE 0001357459 PALISADE BIO, INC. 001-33672 7750 EL CAMINO REAL, SUITE 5200 CARLSBAD CA 92009 (858) 704-4900 Jones Mitchell Lawrence Officer Common Raymond James & Associates

880 Carillon Parkway St. Petersburg FL 33716

53000 108120.00 173580000 07/07/2026 NASDAQ Common 07/07/2026 RSU issuer N 53000 07/07/2026 Cash Y RSU SELL TO COVER FOR TAXES 07/07/2026 Rashida Mitchell, as duly authorized representative of Raymond James & Associates, Inc., as attorney-in-fact for Mitchell Lawrence Jones