X0609 4 2026-10-14 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001226675 GREGORY JULIA P false C/O NURIX THERAPEUTICS, INC. 1600 SIERRA POINT PKWY BRISBANE CA 94005 1 0 0 0 0 Common Stock 2026-10-14 4 M 0 22583 1.86 A 33333 D Common Stock 2026-10-14 4 S 0 22583 23.4038 D 10750 D Director Stock Option (right to buy) 1.86 2026-10-14 4 M 0 22583 0 D 2029-12-22 Common Stock 22583 0 D Represents the weighted average sale price. The lowest price at which shares were sold was $23.34 and the highest price at which shares were sold was $23.62. The Reporting Person undertakes to provide upon request to the staff of the Securities and Exchange Commission, the Issuer or its stockholders, full information regarding the total number of shares sold at each separate price within the range set forth herein. The stock option vested as to 1/48 of the total shares monthly beginning September 12, 2019 until the option was fully vested on August 12, 2023. /s/ Daniel Burbach, as Attorney-in-Fact for Julia P. Gregory 2026-10-14