X0202 SCHEDULE 13G/A 0000019617 XXXXXXXX LIVE 1 Ordinary Shares, par value 0.05 09/30/2026 0001590560 uniQure N.V. N90064101 Paasheuvelweg 25a 1105 BP Amsterdam The Netherlands XX 00000 Rule 13d-1(b) JPMORGAN CHASE & CO. DE 5654307.0 1.0 5943150.0 1.0 5951794.0 8.5 HC uniQure N.V. Paasheuvelweg 25a 1105 BP Amsterdam The Netherlands JPMORGAN CHASE & CO. 270 Park Avenue,,New York, NY 10017 DE N HC 5951794 8.5 5654307 1 5943150 1 Y N N Not Applicable N JPMorgan Asset Management (UK) Limited; JPMorgan Chase Bank, National Association; J.P. Morgan Investment Management Inc.; J.P. Morgan Wealth Management Solutions Inc. N Not Applicable N Not Applicable N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. JPMORGAN CHASE & CO. Rachel Tsvaygoft 10/16/2026