<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001641172-25-010575</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: KEYWELL BRADLEY A -->
          <cik>0001114238</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>Class A Common Stock, par value $0.0001 per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>06/18/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001717115</issuerCik>
        <issuerName>Tempus Al, Inc.</issuerName>
        <issuerCusips>
          <issuerCusipNumber>71535D106</issuerCusipNumber>
        </issuerCusips>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>600 West Chicago Avenue</com:street1>
          <com:street2>Suite 510</com:street2>
          <com:city>Chicago</com:city>
          <com:stateOrCountry>IL</com:stateOrCountry>
          <com:zipCode>60654</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Bradley A. Keywell</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>6071744.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>6071744.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>6071744.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>3.46</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>Mr. Keywell holds these shares indirectly through (i) a grantor retained annuity trust (195,160 shares); (ii) The Keywell Foundation, Inc., a Delaware corporation of which he is President ("KF"). As such, he has sole voting and dispositive power of the shares held by KF; and (iii) BK TL21 LLC, a Delaware limited liability company ("BK") of which he is the sole member and manager. As such, Mr. Keywell holds shared voting and dispositive power over the shares owned by BK; and Churchill Investments 21 LLC, a Delaware limited liability company ("CI"). Mr. Keywell is the managing member of the managing member of CI and as such has shared voting and dispositive control over these shares. The percentage is based on 175,390,967 shares of the issuer's Class A Common Stock, par value $0.0001 per share, outstanding as of July 24, 2026 as reported in the issuer's Quarterly Report on Form 10-Q filed on July 30, 2026.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>BK TL21 LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>2213198.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>2213198.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>2213198.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>1.26</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
      <comments>BK holds these shares directly, and as such, BK holds sole voting and dispositive power over the shares. The percentage is based on 175,390,967 shares of the issuer's Class A Common Stock, par value $0.0001 per share, outstanding as of July 24, 2026 as reported in the issuer's Quarterly Report on Form 10-Q filed on July 30, 2026.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>The Keywell Foundation Inc</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>357900.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>357900.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>357900.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>0.02</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>KF holds these shares directly, and Mr. Keywell as President holds sole voting and dispositive power over these shares. The percentage is based on 175,390,967 shares of the issuer's Class A Common Stock, par value $0.0001 per share, outstanding as of July 24, 2026 as reported in the issuer's Quarterly Report on Form 10-Q filed on July 30, 2026.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Churchill Investments 21 LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>3305486.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>3305486.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3305486.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>1.88</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
      <comments>CF holds these shares directly. Mr. Keywell is the managing member of the managing member of CI and as such has shared voting and dispositive control over these shares. The percentage is based on 175,390,967 shares of the issuer's Class A Common Stock, par value $0.0001 per share, outstanding as of July 24, 2026 as reported in the issuer's Quarterly Report on Form 10-Q filed on July 30, 2026.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Tempus Al, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>600 West Chicago Avenue, Suite 510, Chicago, IL, 60654</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Bradley A. Keywell ("Mr. Keywell"), BK TL21 LLC ("BK"), The Keywell Foundation Inc ("KF") and Churchill Investments 21 LLC ("CI") each a "Reporting Person".</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>Each Reporting Person's principal business address is: 718 Thompson Lane #108-274, Nashville, TN 37204.</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Mr. Keywell is a US citizen, BK is a Delaware limited liability company, KF is a Delaware Corporation and CI is a Delaware limited liability company.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>6,071,744 shares of Class A Common Stock, par value $0.0001.</amountBeneficiallyOwned>
        <classPercent>Less than 5%</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>Mr. Keywell - 0.00 BK - 0.00</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>Mr. Keywell - 6,071,744 BK - 2,213,198 KF - 357,900 CI - 3,305,486</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>Mr. Keywell - 0.00 BK - 0.00</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>Mr. Keywell - 6,071,744 BK - 2,213,198 KF - 357,900 CI - 3,305,486</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>Y</notApplicableFlag>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Bradley A. Keywell</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Bradley A. Keywell</signature>
        <title>Bradley A. Keywell</title>
        <date>10/28/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>BK TL21 LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Bradley A. Keywell</signature>
        <title>Manager</title>
        <date>10/28/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>The Keywell Foundation Inc</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Bradley A Keywell</signature>
        <title>President</title>
        <date>10/28/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Churchill Investments 21 LLC</reportingPersonName>
      <signatureDetails>
        <signature>1 plus 1 Ventures LLC</signature>
        <title>/s/ Bradley A Keywell, Manager</title>
        <date>10/28/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
