144 0001742428 XXXXXXXX LIVE 0001484612 Outset Medical, Inc. 001-39513 3052 ORCHARD DRIVE SAN JOSE CA 95134 669-231-8200 Gaeta Renee Officer Common Stock Morgan Stanley Smith Barney LLC

1 New York Plaza 38th Fl New York NY 10004

4422 19939.32 18800114 08/17/2026 NASDAQ Common Stock 08/15/2026 Settlement of Vested Restricted Stock Units Issuer N 12322 08/17/2026 Equity Compensation for services rendered N Renee Gaeta

3052 Orchard Dr San Jose CA 95134

Common Stock 06/03/2026 17672 87384.92 This sale was made to satisfy tax withholding obligations through a sell to cover transaction in connection with the vesting of Restricted Stock Units and does not represent a discretionary trade by the reporting person. 08/14/2026 /s/ John L Brottem POA