Exhibit 99.2

October 30, 2026

Dear Shareholder,

On behalf of the Board of Directors of MDxHealth SA (the “Company”), you are cordially invited to attend the extraordinary general shareholders’ meeting (“Extraordinary Meeting”) to be held in-person on Thursday, November 19, 2026, at 4:00 p.m. (Belgian time) at the offices of the notary public Stijn Raes, at Kortrijksesteenweg 1147, 9051 Ghent, Belgium.

The agenda, proposed resolution and the other documents for the Extraordinary Meeting are available in French and English on the Company’s website (see: https://www.mdxhealth.com/shareholder-information/). We encourage you to read these materials carefully.

Whether or not you plan to attend the meeting, your vote is important, and we encourage you to vote promptly.

For a description of the formalities to be fulfilled by holders of securities of the Company to participate and vote in an Extraordinary Meeting, please see the notice convening the meeting, which can be found on the Company’s website.

You may also vote your shares through one of the methods described in the accompanying proxy card.

NOTICE OF MDXHEALTH SA
EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS
NOVEMBER 19, 2026 4:00 P.M. (Belgian Time)

At the offices of the notary public Stijn Raes, at Kortrijksesteenweg 1147, 9051 Ghent, Belgium

To the Shareholders of MDxHealth SA:

The extraordinary general shareholders’ meeting (“Extraordinary Meeting”) is to be held in-person on Thursday, November 19, 2026, at 4:00 p.m. Central European Time at the offices of the notary public Stijn Raes, at Kortrijksesteenweg 1147, 9051 Ghent, Belgium.

The purpose of the Extraordinary Meeting is to report on and approve:

The detailed agenda, proposed resolution and the other documents for the Extraordinary Meeting are available in French and English on the Company’s website (see: https://www.mdxhealth.com/shareholder-information/). We encourage you to read these materials carefully.

YOUR VOTE IS IMPORTANT. WHETHER OR NOT YOU PLAN TO ATTEND THE MEETING, PLEASE VOTE YOUR SHARES IN ACCORDANCE WITH THE INSTRUCTIONS SET OUT ON THE ACCOMPANYING PROXY CARD. PROXY CARDS SHOULD BE DATED, SIGNED AND RETURNED FOR RECEIPT BY OR BEFORE NOVEMBER 16, 2026. YOUR PROMPT COOPERATION IS GREATLY APPRECIATED.