X0609 4 2026-10-09 0 0001937993 Cadrenal Therapeutics, Inc. CVKD 0001405290 Pham Quang X false C/O CADRENAL THERAPEUTICS, INC. 822 A1A NORTH, SUITE 306 PONTE VEDRA FL 32082 1 1 1 0 Chairman and CEO 0 Stock Option 0.91 2026-10-09 4 A 0 200000 0 A 2026-10-09 2036-10-08 Common Stock 200000 200000 D The stock options have a grant date of October 9, 2026 under the Issuer's 2022 Successor Equity Incentive Plan, were fully vested and immediately exercisable on the date of grant, and have an exercise price equal to the closing price of the Issuer's common stock on October 9, 2026. /s/ Quang X. Pham 2026-10-13