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Company research

BIOCRYST PHARMACEUTICALS INC

CIK 882796Updated Sep 27, 2026

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About the company

BioCryst is a global biotechnology company focused on developing and commercializing medicines for hereditary angioedema (“HAE”) and other rare diseases, driven by its deep commitment to improving the lives of people living with these conditions. BioCryst has commercialized ORLADEYO® (berotralstat), the first oral, once-daily plasma kallikrein inhibitor, and is advancing a pipeline of potential first-in-class or best-in-class oral small-molecule and injectable protein therapeutics for a range of rare diseases. For more information, please visit www.biocryst.com or follow us on LinkedIn.

8-K · 2026-01-23 · 0001140361-26-002200

Company description from the cited filing.

In the news

Seeking Alpha
SEC disclosures

Financials

FY 2025 · USD
Revenue— · FY 2025
Net income263,861,000USD · FY 2025
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

Operating income340,989,000USD · FY 2025
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

Diluted EPS1.21USD per share · FY 2025
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

Some figures are unavailable for this reporting year.

balance sheet · annual statements
Line itemFY 2025FY 2024FY 2023FY 2022
ASSETS
AssetsUSD514,158,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

490,420,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

516,960,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

550,000,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Property, Plant and Equipment, NetUSD8,783,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

7,777,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

7,910,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

8,617,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Current assets:
Cash and Cash Equivalents, at Carrying ValueUSD89,736,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

104,713,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

110,643,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

304,767,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Accounts Receivable, after Allowance for Credit Loss, CurrentUSD106,818,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

79,069,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

56,950,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

50,599,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Inventory, NetUSD5,398,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

31,274,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

28,683,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

27,533,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Assets, CurrentUSD404,346,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

421,968,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

495,966,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

516,500,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Prepaid Expense and Other Assets, CurrentUSD17,182,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

13,752,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

19,542,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

12,586,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Operating Lease, Right-of-Use AssetUSD7,548,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

8,061,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

8,682,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

6,806,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Other Assets, NoncurrentUSD5,672,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

5,157,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

13,084,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

6,806,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

LIABILITIES AND EQUITY
LiabilitiesUSD633,311,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

966,354,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

——
Stockholders’ equity:
Preferred Stock, Value, IssuedUSD0
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

0
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

0
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

0
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Common Stock, Value, IssuedUSD2,131,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

2,085,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

2,058,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

1,879,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Additional Paid in CapitalUSD1,384,857,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

1,291,100,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

1,222,236,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

1,158,118,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Retained Earnings (Accumulated Deficit)USD-1,506,179,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

-1,770,040,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

-1,681,159,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

-1,454,620,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Accumulated Other Comprehensive Income (Loss), Net of TaxUSD38,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

921,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

1,337,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

26,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Stockholders' Equity Attributable to ParentUSD-119,153,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

-475,934,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

-455,528,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

-294,597,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Liabilities and EquityUSD514,158,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

490,420,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

516,960,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

550,000,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Current liabilities:
Liabilities, CurrentUSD196,066,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

160,384,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

149,988,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

105,514,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Operating Lease, Liability, CurrentUSD317,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

937,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

1,058,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

2,369,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Accounts Payable, CurrentUSD15,826,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

11,644,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

20,893,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

14,356,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Operating Lease, Liability, NoncurrentUSD8,571,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

7,924,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

8,390,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

5,804,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Additional Financial Items
Accrued Liabilities, CurrentUSD126,413,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

113,292,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

102,882,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

87,565,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Deferred Revenue, CurrentUSD——0
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

1,224,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Deferred Tax Liabilities, NetUSD———11,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Long-term Debt, Excluding Current MaturitiesUSD0
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

314,869,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

As of 2024-12-31

303,231,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

As of 2023-12-31

231,624,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

As of 2022-12-31

Short-term InvestmentsUSD185,011,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

———

Lines labelled “Derived” are calculated from reported figures.

cash flow · annual statements
Line itemFY 2025FY 2024FY 2023FY 2022
Cash flows from operating activities:
Adjustments to reconcile net income to net cash provided by operating activities:
Depreciation, Depletion and AmortizationUSD1,389,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

1,246,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

1,655,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

1,437,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Share-based Payment Arrangement, Noncash ExpenseUSD85,066,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

65,413,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

55,615,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

44,701,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Changes in operating assets and liabilities:
Increase (Decrease) in InventoriesUSD1,639,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

4,164,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

1,450,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

12,423,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Increase (Decrease) in Accounts PayableUSD57,802,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-62,379,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-16,806,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-22,360,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Deferred Income Tax Expense (Benefit)USD-1,212,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-354,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-682,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

—
Net Cash Provided by (Used in) Operating ActivitiesUSD347,369,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-52,020,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-95,141,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-161,850,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Cash flows from investing activities:
Net Cash Provided by (Used in) Investing ActivitiesUSD-13,694,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

52,593,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-131,498,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-128,238,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Cash flows from financing activities:
Payment, Tax Withholding, Share-based Payment ArrangementUSD8,847,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

7,535,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

2,172,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

—
Net Cash Provided by (Used in) Financing ActivitiesUSD-349,931,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-5,761,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

32,485,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

88,027,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Repayments of Long-term DebtUSD300,000,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate EffectUSD-14,986,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-6,124,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-193,792,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-201,495,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Cash, Cash Equivalents, Restricted Cash and Restricted Cash EquivalentsUSD91,337,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

As of 2025-12-31

———
Supplemental disclosure of cash flow information:
Interest Paid, Excluding Capitalized Interest, Operating ActivitiesUSD23,735,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

30,383,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

22,139,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

—
Income Taxes Paid, NetUSD2,803,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———
Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash and Restricted Cash EquivalentsUSD1,270,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-936,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

362,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

566,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Additional Financial Items
Share-based Payment Arrangement, ExpenseUSD85,066,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

65,413,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

55,615,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

44,701,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Gain (Loss) on Disposition of BusinessUSD3,566,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———
Gain (Loss) on Disposition of Other AssetsUSD550,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———
Gain (Loss) on Extinguishment of DebtUSD-17,332,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

0
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-29,019,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

0
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Income Tax Expense (Benefit)USD3,530,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

1,927,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

310,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

2,733,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

InterestExpenseNonoperatingUSD78,872,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

98,516,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

——
Inventory Write-downUSD985,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

1,350,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

422,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

932,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Net Income (Loss) Attributable to ParentUSD263,861,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-88,881,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-226,539,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-247,116,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Nonoperating Income (Expense)USD-73,598,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-84,411,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

——
Operating Lease, ExpenseUSD2,007,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

2,301,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

2,018,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

2,532,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Payments of Financing CostsUSD———34,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Proceeds from Issuance of Common StockUSD——0
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

0
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Proceeds from Issuance of Long-term DebtUSD0
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

0
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

300,000,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

—
Proceeds from Stock Options ExercisedUSD———14,955,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Restructuring CostsUSD6,314,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———
Revenue from Contract with Customer, Including Assessed TaxUSD874,837,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

450,712,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

331,412,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

270,827,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Share-based Payment Arrangement, Expensed and Capitalized, AmountUSD85,137,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———

Lines labelled “Derived” are calculated from reported figures.

income statement · annual statements
Line itemFY 2025FY 2024FY 2023FY 2022
Cost of RevenueUSD19,075,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

12,269,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

4,481,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

6,408,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Selling, General and Administrative ExpenseUSD348,647,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

266,132,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

213,894,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

159,371,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Operating Income (Loss)USD340,989,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-2,543,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-103,709,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-148,435,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling InterestUSD267,391,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-86,954,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-226,229,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-244,383,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Income Tax Expense (Benefit)USD3,530,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

1,927,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

310,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

2,733,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Net Income (Loss) Attributable to ParentUSD263,861,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-88,881,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-226,539,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-247,116,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Earnings Per Share, BasicUSD per share1.26
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-0.43
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-1.18
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-1.33
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Earnings Per Share, DilutedUSD per share1.21
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-0.43
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-1.18
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-1.33
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Weighted Average Number of Shares Outstanding, Basicshares209,893,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

206,696,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

192,198,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

185,908,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Weighted Average Number of Shares Outstanding, Dilutedshares218,581,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

206,696,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

192,198,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

185,908,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Interest Expense (non-operating)USD78,872,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

98,516,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

——
Additional Financial Items
Costs and ExpensesUSD533,848,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

453,255,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

435,121,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

419,262,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Current Income Tax Expense (Benefit)USD4,742,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

2,281,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

992,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

2,722,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Income (Loss) from Continuing Operations before Income Taxes, DomesticUSD172,638,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-62,515,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

-206,674,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

-225,127,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Interest and Other IncomeUSD10,668,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

14,746,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

——
Interest ExpenseUSD——108,239,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

99,092,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Interest Expense, DebtUSD———99,092,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Nonoperating Income (Expense)USD-73,598,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

-84,411,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

——
Operating Lease, ExpenseUSD2,007,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

2,301,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

2,018,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

2,532,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Other IncomeUSD12,090,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———
Research and Development ExpenseUSD166,126,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

174,638,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

216,566,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

253,297,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Restructuring CostsUSD6,314,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———
Revenue from Contract with Customer, Including Assessed TaxUSD874,837,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

450,712,000
Source

10-K · 2025-02-25 · 0001628280-25-007715

2024-01-01 to 2024-12-31

331,412,000
Source

10-K · 2024-02-27 · 0001628280-24-007205

2023-01-01 to 2023-12-31

270,827,000
Source

10-K · 2023-02-27 · 0001628280-23-005259

2022-01-01 to 2022-12-31

Share-based Payment Arrangement, Expensed and Capitalized, AmountUSD85,137,000
Source

10-K · 2026-02-26 · 0001628280-26-012240

2025-01-01 to 2025-12-31

———

Lines labelled “Derived” are calculated from reported figures.

Offerings

Registration 333-291678

S-4/A · 2025-12-15 · 0001140361-25-045461

Terms from the governing filing for this registration; not a claim that the offering is open today.

Filing attachments

ef20063492_ex99-1.htm · 8-K · 2026-01-23

EX-99.1 2 ef20063492_ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 BioCryst Completes Acquisition of Astria Therapeutics, Expanding Leadership in Hereditary Angioedema RESEARCH TRIANGLE PARK, N.C. - January 23, 2026 - BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that it has completed its acquisition of Astria Therapeutics, Inc., initially announced on October 14, 2025. The transaction strengthens its position as a leader in hereditary angioedema (HAE) and enhances the company’s lon…

8-K · 2026-01-23 · 0001140361-26-002200

Read attachment ↗
ef20063492_ex99-2.htm · 8-K · 2026-01-23

EX-99.2 3 ef20063492_ex99-2.htm EXHIBIT 99.2 Exhibit 99.2 Astria Therapeutics, Inc. Condensed Consolidated Balance Sheets (In thousands, except share and per share data) (Unaudited) September 30, December 31, …

8-K · 2026-01-23 · 0001140361-26-002200

Read attachment ↗
ny20057110x2_ex99-2.htm · S-4/A · 2025-12-15

EX-99.2 5 ny20057110x2_ex99-2.htm EXHIBIT 99.2 Exhibit 99.2 Consent of Evercore Group L.L.C. December 15, 2025 Astria Therapeutics, Inc. 22 Boston Wharf Road, 10th Floor Boston, MA 02210 Members of the Board of Directors: We hereby consent to the inclusion of our opinion letter, dated October 13, 2025, to the Board of Directors of Astria Therapeutics, Inc. (“Astria”), as Annex C to, and reference thereto under the captions “Summary-Opinion of Astria’s Financial Advisor “, “The Merger-…

S-4/A · 2025-12-15 · 0001140361-25-045461

Read attachment ↗
ef20060538_ex99-1.htm · 8-K · 2025-12-03

EX-99.1 2 ef20060538_ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 BioCryst Receives Early Termination of HSR Waiting Period for Astria Acquisition RESEARCH TRIANGLE PARK, N.C. - December 3, 2025 - BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that it has received early termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended (the “HSR Act”), with respect to BioCryst’s proposed acquisition of Astria Therapeutics, Inc. (the “Merger”…

8-K · 2025-12-03 · 0001140361-25-044110

Read attachment ↗
ny20057110x1_ex99-2.htm · S-4 · 2025-11-20

EX-99.2 5 ny20057110x1_ex99-2.htm EXHIBIT 99.2 Exhibit 99.2 Consent of Evercore Group L.L.C. November 20, 2025 Astria Therapeutics, Inc. 22 Boston Wharf Road, 10th Floor Boston, MA 02210 Members of the Board of Directors: We hereby consent to the inclusion of our opinion letter, dated October 13, 2025, to the Board of Directors of Astria Therapeutics, Inc. (“Astria”), as Annex C to, and reference thereto under the captions “Summary- Opinion of Astria’s Financial Advisor ”, “The Merger…

S-4 · 2025-11-20 · 0001140361-25-042879

Read attachment ↗
ef20057029_ex99-1.htm · 8-K · 2025-10-14

EX-99.1 3 ef20057029_ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 VOTING AND SUPPORT AGREEMENT among BIOCRYST PHARMACEUTICALS, INC. and certain stockholders of ASTRIA THERAPEUTICS, INC. Dated as of October 14, 2025 VOTING AND SUPPORT AGREEMENT dated as of October 14, 2025 (this “Agreement”), among BioCryst Pharmaceuticals, Inc., a Delaware corporation (“Parent”) and each of the signatories named on the signature pages hereto (each, a “Stockholder” and, collectively, the “Stockholders”). Int…

8-K · 2025-10-14 · 0001140361-25-038031

Read attachment ↗