INTERPACE BIOSCIENCES INC

Item 5.03. Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year. At the annual meeting of stockholders held on August 20, 2026, the stockholders of Interpace Biosciences, Inc. (the “Company”) authorized the board of directors of the Company (the “Board”), in its discretion, to amend the Company’s Amended and Restated Certificate of Incorporation (the “Certificate of Incorporation”), to effect a reverse split of the Company’s outstanding common stock, par value $0.01 (the “Common Stock”), at a ratio between one-for-two (1:2) and one-for-ten (1:10), with such final ratio to be determined by the Board. The Board determined to set the reverse stock split ratio at one-for-five (1:5) (the “Reverse Stock Split”) and approved the final form of the Certificate of Amendment to the Certificate of Incorporation to effectuate the Reverse Stock Split (the “Certificate of Amendment”). The Certificate of Amendment was filed with the Secretary of State of the State of Delaware on August 25, 2026, and the Reverse Stock Split will become effective in accordance with the terms of the Certificate of Amendment at 12:01 a.m. Eastern Time on Thursday, August 27, 2026 (the “Effective Time”). At the Effective Time, every five shares of Common Stock issued and outstanding will be automatically combined into one share of issued and outstanding Common Stock, without any change in the par value per share. Fractional shares will not be issued as a result of the Reverse Stock Split. Instead, any fractional shares of the Company’s Common Stock that would have otherwise resulted from the Reverse Stock Split will be rounded up to the nearest whole share. Stockholders who are holding their shares of Common Stock electronically in direct registered book-entry form with Equiniti Trust Company, LLC, the Company’s transfer agent (the “Transfer Agent”), or in “street name” (through a broker, bank or other holder of record) will not need to take action. The Reverse Stock Split will automatically be reflected in the Transfer Agent’s records and on such stockholders’ next account statement. Stockholders holding paper certificates that are issued and outstanding and were not exchanged as part of previous corporate actions will be automatically canceled and exchanged for book-entry shares. The Common Stock is expected to begin trading on the OTCID quotation system (“OTCID”) on a Reverse Stock Split - adjusted basis as of the commencement of market open on Thursday, August 27, 2026. Interpace’s ticker symbol on the OTCID will temporarily change to IDXGD for a period of 20 trading days, including the effective date. In connection with the Reverse Stock Split, the CUSIP number for the Common Stock has been changed to 46062X 402. The Reverse Stock Split will result in a proportionate adjustment to the per share exercise price and the number of shares of Common Stock issuable upon the exercise of outstanding stock options, as well as the number of shares of Common Stock eligible for issuance under the Company’s newly adopted 2026 Incentive Stock Plan and 2026 Employee Stock Purchase Plan (as defined in the Company’s Current Report on Form 8-K/A filed with the Security Exchange Commission on August 26, 2026). The information set forth herein does not purport to be complete and is qualified in its entirety by reference to the full text of the form of Certificate of Amendment that effectuated the Reverse Stock Split, which is filed as Exhibit 3.1 hereto and incorporated herein by reference.

Item 7.01. Regulation FD Disclosure. On August 26, 2026, the Company issued a press release announcing the Reverse Stock Split. A copy of the press release is attached as Exhibit 99.1 hereto. The information furnished pursuant to this Item 7.01, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities under that Section and shall not be deemed to be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.