COMERICA INC

ITEM 3.03 MATERIAL MODIFICATION TO RIGHTS OF SECURITY HOLDERS. On August 11, 2025, Comerica Incorporated (the “Company”) issued and sold 16,000,000 depositary shares (the “Depositary Shares”), each representing a 1/40th ownership interest in a share of 6.875% Fixed-Rate Reset Non-Cumulative Perpetual Preferred Stock, Series B, no par value per share, with a liquidation preference of $1,000 per share (equivalent to $25 per Depositary Share) (the “Series B Preferred Stock”). The Company filed a Certificate of Designations (the “Certificate of Designations”) with the Secretary of State of the State of Delaware establishing the voting powers, designations, preferences and relative participating, optional and other special rights, and qualifications, limitations or restrictions thereof, of the Series B Preferred Stock on August 7, 2025. Holders of the Depositary Shares are entitled to all proportional rights and preferences of the Series B Preferred Stock (including dividend, voting, redemption and liquidation rights). Under the terms of the Series B Preferred Stock, the ability of the Company to pay dividends on, make distributions with respect to, or repurchase, redeem or acquire the Company’s common stock or any other stock ranking on parity with or junior to the Series B Preferred Stock, is subject to restrictions in the event that the Company does not declare and either pay or set aside a sum sufficient for payment of dividends on the Series B Preferred Stock for the immediately preceding dividend period. The foregoing description of the Series B Preferred Stock does not purport to be complete and is qualified in its entirety by reference to the Certificate of Designations. A copy of the Certificate of Designations, to which the form of certificate representing the Series B Preferred Stock is attached as Exhibit A, is filed as Exhibit 3.1 to this Current Report on Form 8-K and is incorporated by reference herein.

ITEM 5.03 AMENDMENTS TO ARTICLES OF INCORPORATION OR BYLAWS; CHANGE IN FISCAL YEAR. The Certificate of Designations became effective upon filing with the Secretary of State of the State of Delaware, and it amends the Company’s Restated Certificate of Incorporation, as amended. The terms of the Series B Preferred Stock are more fully described in Item 3.03 of this Current Report on Form 8-K, which is incorporated by reference herein.

ITEM 8.01 OTHER EVENTS. On August 4, 2025, the Company entered into an Underwriting Agreement (the “Underwriting Agreement”) with BofA Securities, Inc., J.P. Morgan Securities LLC, Morgan Stanley & Co. LLC and RBC Capital Markets, LLC, as the representatives of the several underwriters named therein (collectively, the “Underwriters”), under which the Company agreed to sell to the Underwriters 16,000,000 Depositary Shares, each representing a 1/40th ownership interest in a share of Series B Preferred Stock. The Underwriting Agreement contains various representations, warranties and agreements by the Company and indemnification rights and obligations of the parties. The foregoing description of the Underwriting Agreement does not purport to be complete and is qualified in its entirety by reference to the Underwriting Agreement, a copy of which is filed as Exhibit 1.1 to this Current Report on Form 8-K and is incorporated by reference herein. The Depositary Shares were issued pursuant to a Deposit Agreement, dated August 11, 2025, by and among the Company, Computershare Inc. and Computershare Trust Company, N.A. and the holders from time to time of the depositary receipts issued thereunder (the “Deposit Agreement”). A copy of the Deposit Agreement, to which the form of depositary receipt is attached as Exhibit A, is filed as Exhibit 4.2 to this Current Report on Form 8-K and is incorporated by reference herein. The net proceeds to the Company from the offering of the 16,000,000 Depositary Shares were approximately $392.2 million, after deducting the underwriting discount and estimated offering expenses payable by the Company. The offering was made pursuant to the prospectus supplement dated August 4, 2025 and the accompanying prospectus dated February 9, 2024, filed with the Securities and Exchange Commission pursuant to the Company’s effective registration statement on Form S-3 (File No. 333-277000) (the “Registration Statement”). The following documents are being filed with this Current Report on Form 8-K and are incorporated by reference into the Registration Statement: (a) the Underwriting Agreement, (b) the Certificate of Designations, to which the form of certificate representing the Series B Preferred Stock is attached as Exhibit A, (c) the Deposit Agreement, to which the form of depositary receipt is attached as Exhibit A and (d) a validity opinion with respect to the Depositary Shares and the Series B Preferred Stock.