Cisco Systems, Inc.

Item 1.01 Entry into a Material Definitive Agreement. On February 24, 2025, Cisco Systems, Inc. (the “Company”) issued $1,000,000,000 principal amount of its 4.550% Senior Notes due 2028 (the “2028 Notes”), $1,000,000,000 principal amount of its 4.750% Senior Notes due 2030 (the “2030 Notes”), $1,000,000,000 principal amount of its 4.950% Senior Notes due 2032 (the “2032 Notes”), $1,250,000,000 principal amount of its 5.100% Senior Notes due 2035 (the “2035 Notes”) and $750,000,000 principal amount of its 5.500% Senior Notes due 2055 (the “2055 Notes” and, together with the 2028 Notes, the 2030 Notes, the 2032 Notes and the 2035 Notes, the “Notes”). The Notes are governed by an Indenture, dated as of February 26, 2024 (the “Base Indenture”), between the Company and The Bank of New York Mellon Trust Company, N.A., the trustee (the “Trustee”), as supplemented by the Second Supplemental Indenture, dated as of February 24, 2025 (the “Second Supplemental Indenture” and, together with the Base Indenture, the “Indenture”), between the Company and the Trustee. The Notes were sold pursuant to an underwriting agreement, dated February 19, 2025 (the “Underwriting Agreement”), among the Company and BNP Paribas Securities Corp., Goldman Sachs & Co. LLC, HSBC Securities (USA) Inc., Morgan Stanley & Co. LLC and Wells Fargo Securities, LLC on behalf of the several underwriters named therein. The Company intends to use the proceeds from this offering for general corporate purposes, including the repayment of commercial paper borrowings. The Notes were offered pursuant to the Company’s Registration Statement on Form S-3 (File No. 333-277109) filed with the Securities and Exchange Commission (the “SEC”), as supplemented by the prospectus supplement dated February 19, 2025 relating to the Notes. The 2028 Notes mature on February 24, 2028, the 2030 Notes mature on February 24, 2030, the 2032 Notes mature on February 24, 2032, the 2035 Notes mature on February 24, 2035 and the 2055 Notes mature on February 24, 2055. The 2028 Notes will bear interest from February 24, 2025 at the rate of 4.550% per annum, payable semiannually, the 2030 Notes will bear interest from February 24, 2025 at the rate of 4.750% per annum, payable semiannually, the 2032 Notes will bear interest from February 24, 2025 at the rate of 4.950% per annum, payable semiannually, the 2035 Notes will bear interest from February 24, 2025 at the rate of 5.100% per annum, payable semiannually and the 2055 Notes will bear interest from February 24, 2025 at the rate of 5.500% per annum, payable semiannually. The Company will have the option to redeem the 2028 Notes, the 2030 Notes, the 2032 Notes, the 2035 Notes and the 2055 Notes, in whole or in part, (i) at any time at the applicable make-whole premium redemption price or (ii) at a redemption price equal to 100% of the principal amount of the Notes being redeemed, with respect to the 2028 Notes, beginning on January 24, 2028 (one month prior to the maturity date of such Notes), with respect to the 2030 Notes, beginning on January 24, 2030 (one month prior to the maturity date of such Notes), with respect to the 2032 Notes, beginning on December 24, 2031 (two months prior to the maturity date of such Notes), with respect to the 2035 Notes, beginning on November 24, 2034 (three months prior to the maturity date of such Notes) and with respect to the 2055 Notes, beginning on August 24, 2054 (six months prior to the maturity date of such Notes), in each case including accrued interest to but excluding the relevant redemption date. The Notes are unsecured and will rank equally in right of payment with all of our other existing and future senior unsecured indebtedness. The Notes will effectively rank junior to all liabilities of our subsidiaries. The Indenture governing the Notes contains covenants limiting our ability to consolidate with or into another person, or sell, transfer or lease or convey all or substantially all our properties and assets to another person. Events of default under the Indenture include, among others, the following (subject in certain cases to grace and cure periods): nonpayment of interest and principal on the Notes after becoming due and breach of covenants contained in the Indenture. The foregoing descriptions of the Underwriting Agreement, the Base Indenture and the Second Supplemental Indenture (including the forms of the Notes) are qualified in their entirety by the terms of such agreements. Please refer to such agreements, each of which are incorporated herein by reference and attached hereto as Exhibits 1.1, 4.1 and 4.2, respectively.

Item 2.03 Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant. The information provided in Item 1.01 of this Report is incorporated by reference into this Item 2.03.