Notice of Proposed Sale · 144

BEONE MEDICINES LTD

Notice of Proposed Sale

Filed Jul 14, 2026Accepted Jul 14, 2026, 4:48 PM EDTFiling CIK 1042047Accession 0001950047-26-007070

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer: BEONE MEDICINES LTD
Issuer CIK: 0001651308
SEC file number: 001-37686
Phone: 41616851900
Person for whose account securities are to be sold: JOHN V OYLER
Relationships to issuer: Director · Officer
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Securities proposed for sale

Securities proposed for sale · 1 reported row
Security	Proposed units	Aggregate market value	Units outstanding	Approximate sale date	Exchange	Broker / market maker
ADS	513,574	156,105,953.04	54,885,669	07/14/2026	NASDAQ	Morgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name: Morgan Stanley Smith Barney LLC Executive Financial Services
Street: 1 New York Plaza
Street (continued): 8th Floor
City: New York
State / country code: NY
Postal code: 10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 3 reported rows
Security	Acquired	Nature of acquisition	Acquired from	Amount acquired	Gift transaction	Payment date	Nature of payment
ADS	07/14/2026	Exercise of Stock Options	Issuer	425,590	N	07/14/2026	Cash
ADS	03/03/2025	Previously Exercised Stock Options	Issuer	75,723	N	03/03/2025	Cash
ADS	06/05/2026	Restricted Stock Units	Issuer	12,261	N	06/05/2026	N/A

Sales reported in the preceding three months

Sales reported in the preceding three months · 8 reported rows
Seller	Security	Sale date	Amount sold	Gross proceeds
10b5-1 Sales for JOHN OYLER	ADS	07/13/2026	48,520	14,766,882.48
10b5-1 Sales for PAN-OYLER FOUNDATIONC/O JOHN OYLER &MICHAEL SCHOEN	ADS	07/13/2026	37,722	11,483,218.07
10b5-1 Sales for JOHN OYLER	ADS	07/10/2026	11,698	3,489,925.17
10b5-1 Sales for PAN-OYLER FOUNDATIONC/O JOHN OYLER &MICHAEL SCHOEN	ADS	07/10/2026	11,819	3,525,783.80
JOHN V OYLER	Common	06/23/2026	3,410	933,592.21
JOHN V OYLER	Common	06/16/2026	3,693	980,686.48
JOHN V OYLER	Common	06/11/2026	1,949	501,354.72
JOHN V OYLER	Common	06/08/2026	4,940	1,336,566.40

Seller — prior-sale row 1, entry 1

Name: 10b5-1 Sales for JOHN OYLER
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Seller — prior-sale row 2, entry 1

Name: 10b5-1 Sales for PAN-OYLER FOUNDATIONC/O JOHN OYLER &MICHAEL SCHOEN
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Seller — prior-sale row 3, entry 1

Name: 10b5-1 Sales for JOHN OYLER
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Seller — prior-sale row 4, entry 1

Name: 10b5-1 Sales for PAN-OYLER FOUNDATIONC/O JOHN OYLER &MICHAEL SCHOEN
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Seller — prior-sale row 5, entry 1

Name: JOHN V OYLER
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Seller — prior-sale row 6, entry 1

Name: JOHN V OYLER
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Seller — prior-sale row 7, entry 1

Name: JOHN V OYLER
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Seller — prior-sale row 8, entry 1

Name: JOHN V OYLER
Street: Aeschengraben 27
City: Basel
State / country code: V8
Postal code: 4051

Prior-sale reporting

Nothing to report for the preceding three months: N

Remarks

The 425,590 securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale. The 12,261 securities to be sold were acquired upon the vesting of restricted stock units during the period of 06/05/2026 through 06/22/2026.

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