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BCS

Notice of Proposed Sale · 144

Tectonic Therapeutic, Inc.

TECXNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Aug 27, 2026Accepted Aug 27, 2026, 5:20 PM EDTFiling CIK 1117003Accession 0001950047-26-008795
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Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
TECTONIC THERAPEUTIC, INC.
Issuer CIK
0001681087
SEC file number
001-38537
Phone
(339) 666-3320
Person for whose account securities are to be sold
TERRANCE MCGUIRE
Relationships to issuer
Former Director
Street
490 ARSENAL WAY
Street (continued)
SUITE 200
City
WATERTOWN
State / country code
MA
Postal code
02472

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Common7,513276,718.0619,549,36608/27/2026NASDAQMorgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name
Morgan Stanley Smith Barney LLC Executive Financial Services
Street
1 New York Plaza
Street (continued)
8th Floor
City
New York
State / country code
NY
Postal code
10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Common08/27/2026Stock Option ExerciseIssuer7,513N08/27/2026Cash

Sales reported in the preceding three months

Sales reported in the preceding three months · 1 reported row
SellerSecuritySale dateAmount soldGross proceeds
TERRANCE MCGUIRECommon08/21/202610,200383,670.96

Seller — prior-sale row 1, entry 1

Name
TERRANCE MCGUIRE
Street
490 ARSENAL WAY
Street (continued)
SUITE 200
City
WATERTOWN
State / country code
MA
Postal code
02472

Prior-sale reporting

Nothing to report for the preceding three months
N

Notice signature

Notice date
08/27/2026
Signed
/s/ TERRANCE GERARD MCGUIRE

Company context

Tectonic Therapeutic is a clinical-stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of GPCRs. Leveraging its proprietary technology platform called GEODe™ (GPCRs Engineered for Optimal Discovery), Tectonic is focused on developing biologic medicines that overcome the existing challenges of GPCR-targeted drug discovery and harness the human body to modify the course of disease. Tectonic focuses on areas of significant unmet medical need, often where therapeutic options are poor or nonexistent, as these are areas where new medicines have the potential to improve patient quality of life. Tectonic is headquartered in Watertown, Massachusetts. For more information, please visit https://tectonictx.com/ and follow us on LinkedIn.

Current securities

Recent company filings

  1. 144 filingSep 30, 2026
  2. Other EventsSep 29, 2026
  3. 10-Q filingAug 6, 2026
  4. Results of Operations and Financial ConditionAug 6, 2026
  5. Submission of Matters to a Vote of Security Holders · Other EventsJun 10, 2026

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