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BCS

Notice of Proposed Sale · 144

Madrigal Pharmaceuticals, Inc.

MDGLNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Jul 20, 2026Accepted Jul 20, 2026, 9:11 PM EDTFiling CIK 1157601Accession 0001628280-26-048913
Share

Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
Madrigal Pharmaceuticals, Inc.
Issuer CIK
0001157601
Phone
267-824-2827
Person for whose account securities are to be sold
William Sibold
Relationships to issuer
Officer and Director
Street
1001 Conshohocken State Road
Street (continued)
Suite 2-350
City
West Conshohocken
State / country code
PA
Postal code
19428

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Common Stock2,5001,383,70023,055,65907/20/2026Nasdaq Stock MarketMorgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name
Morgan Stanley Smith Barney LLC Executive Financial Services
Street
1 New York Plaza, 8th Floor
City
New York
State / country code
NY
Postal code
10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Common Stock07/17/2026Performance Restricted Stock Unit GrantIssuer2,500N07/17/2026Vesting of Performance Restricted Stock Units

Prior-sale reporting

Nothing to report for the preceding three months
Y

Remarks

The sale of shares of common stock reported on this Form 144 represents the sale of shares pursuant to a sell-to-cover transaction in order to satisfy certain tax withholding obligations in connection with the Reporting Owner earning Performance Restricted Stock Units previously granted to the Reporting Owner in September 2023.

Notice signature

Notice date
07/20/2026
Signed
/s/ William Sibold

Company context

Madrigal Pharmaceuticals, Inc. (Nasdaq: MDGL) is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a liver disease with high unmet medical need. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by the FDA for the treatment of MASH with moderate to advanced fibrosis (consistent with stages F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (consistent with stage F4c). For more information, visit www.madrigalpharma.com.

Current securities

Recent company filings

  1. 144 filingSep 11, 2026
  2. 144 filingSep 9, 2026
  3. 144 filingAug 20, 2026
  4. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements · Regulation FD DisclosureAug 12, 2026
  5. Results of Operations and Financial ConditionJul 30, 2026

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