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BCS

Changes in Beneficial Ownership · 4

Opus Genetics, Inc.

IRDNASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Oct 27, 2026Accepted Oct 27, 2026, 4:47 PM EDTFiling CIK 1228627Accession 0001140361-26-040908
Share

Structured filing — 4

form4.xml

Open full document ↗

Filing details

Report period
2026-10-23
Issuer
Opus Genetics, Inc.
Issuer CIK
0001228627
Trading symbol
IRD

Reporting owner 1

Name
SCHACHLE JOSEPH K
Reporting owner CIK
0001145914
Relationship
Officer
Officer title
Chief Operating Officer
Address
C/O OPUS GENETICS, INC., 8 DAVIS DRIVE, SUITE 220, DURHAM, NC, 27713

Non-derivative transactions

Non-derivative transactions · 1 reported row
SecurityTransaction dateCodeAmountA / DPrice (USD)Owned afterOwnership
Common Stock2026-10-23S · Form 4[F1]4,767D3.565286,673D
Table key
S · Form 4
Sale on the market or privately
D
Direct

Footnotes

F1
The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Issuer to satisfy tax withholding obligations that arose in connection with the vesting and settlement of restricted stock units. This transaction does not represent a discretionary trade by the Reporting Person.↩ 1

Signature 1

Signed
/s/ Amy Rabourn, by Power of Attorney
Date
2026-10-27

Company context

Opus Genetics is a clinical-stage biopharmaceutical company developing gene therapies to restore vision and prevent blindness in patients with inherited retinal diseases (IRDs). The Company is developing durable, one-time treatments designed to address the underlying genetic causes of severe retinal disorders. The Company’s pipeline includes seven AAV-based programs, led by OPGx-LCA5 for LCA5-related mutations and OPGx-BEST1 for BEST1-related retinal degeneration, with additional candidates targeting RDH12, MERTK, RHO, CNGB1 and NMNAT1. The Company is based in Research Triangle Park, NC. For more information, visit www.opusgtx.com.

Current securities

Historical securities (1)

Recent company filings

  1. 4 filingOct 27, 2026
  2. 144 filingOct 23, 2026
  3. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory ArrangementsOct 21, 2026
  4. Regulation FD DisclosureOct 15, 2026
  5. Regulation FD DisclosureSep 11, 2026

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