Notice of Proposed Sale · 144

Jazz Pharmaceuticals plc

JAZZNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Aug 31, 2026Accepted Aug 31, 2026, 3:10 PM EDTFiling CIK 1232524Accession 0001193210-26-000023

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Structured filing — 144

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer: Jazz Pharmaceuticals plc
Issuer CIK: 0001232524
SEC file number: 001-33500
Phone: 353-1-634-7800
Person for whose account securities are to be sold: COZADD BRUCE C
Relationships to issuer: Director
Street: FIFTH FLOOR, WATERLOO EXCHANGE
Street (continued): WATERLOO ROAD
City: DUBLIN
State / country code: L2
Postal code: D04 E5W7

Securities proposed for sale

Securities proposed for sale · 1 reported row
Security	Proposed units	Aggregate market value	Units outstanding	Approximate sale date	Exchange	Broker / market maker
Common	2,506	612,817.00	64,914,577	08/31/2026	NASDAQ	ETRADE FINANCIAL CORPORATION

Broker / market maker — proposed row 1, entry 1

Name: ETRADE FINANCIAL CORPORATION
Street: 3 EDISON DRIVE
City: ALPHARETTA
State / country code: GA
Postal code: 30005

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
Security	Acquired	Nature of acquisition	Acquired from	Amount acquired	Gift transaction	Payment date	Nature of payment
COMMON	08/28/2026	RESTRICTED STOCK VESTING	ISSUER	2,506	N	08/28/2026	Compensation

Sales reported in the preceding three months

Sales reported in the preceding three months · 3 reported rows
Seller	Security	Sale date	Amount sold	Gross proceeds
COZADD BRUCE C.	COMMON	08/03/2026	6,000	1,517,880.00
COZADD BRUCE C.	COMMON	07/01/2026	6,000	1,442,820.00
COZADD BRUCE C.	COMMON	06/01/2026	6,000	1,410,720.00

Seller — prior-sale row 1, entry 1

Name: COZADD BRUCE C.
Street: 3000 El Camino Real
Street (continued): 2 Palo Alto Square, Suite 600
City: Palo Alto
State / country code: CA
Postal code: 94306

Seller — prior-sale row 2, entry 1

Name: COZADD BRUCE C.
Street: 3000 El Camino Real
Street (continued): 2 Palo Alto Square, Suite 600
City: Palo Alto
State / country code: CA
Postal code: 94306

Seller — prior-sale row 3, entry 1

Name: COZADD BRUCE C.
Street: 3000 El Camino Real
Street (continued): 2 Palo Alto Square, Suite 600
City: Palo Alto
State / country code: CA
Postal code: 94306

Prior-sale reporting

Nothing to report for the preceding three months: N

Notice signature

Notice date: 08/31/2026
Signed: /s/Paz Dizon by power of attorney for Bruce C. Cozadd

Company context

Jazz Pharmaceuticals plc (Nasdaq: JAZZ) is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with rare diseases - often with limited or no therapeutic options. We have a diverse portfolio of medicines, including leading therapies addressing epilepsies, cancers and sleep disorders. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide.

Current securities

JAZZNASDAQ · EQUITY · Current

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