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BCS

Changes in Beneficial Ownership · 4

Tvardi Therapeutics, Inc.

TVRDNASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Jun 11, 2026Accepted Jun 11, 2026, 4:30 PM EDTFiling CIK 1346830Accession 0001201256-26-000003
Share

Structured filing — 4

form4-06112026_040613.xml

Open full document ↗

Filing details

Report period
2026-06-09
Issuer
Tvardi Therapeutics, Inc.
Issuer CIK
0001346830
Trading symbol
TVRD

Reporting owner 1

Name
WYZGA MICHAEL S
Reporting owner CIK
0001201256
Relationship
Director
Address
C/O TVARDI THERAPEUTICS, INC., 3 SUGAR CREEK CTR BLVD, STE 525, SUGAR LAND, TX, 77478

Derivative transactions

Derivative transactions · 1 reported row
SecurityConversion / exercise price (USD)Transaction dateCodeAmountA / DPrice (USD)ExercisableExpiresUnderlying securityUnderlying sharesOwned afterOwnership
Stock Option (right to buy)2.782026-06-09A · Form 46,000A0[F1]2036-06-08Common Stock6,0006,000D
Table key
A · Form 4
Acquisition by grant, award or otherwise under Rule 16b-3(d)
A
Acquired
D
Direct

Footnotes

F1
100% of the shares underlying the option shall vest on the earlier of June 9, 2027 or the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continuous service through such vesting date.↩ 1

Signature 1

Signed
/s/ Dan Conn, Attorney-in-Fact
Date
2026-06-11

Company context

Tvardi is a clinical-stage biopharmaceutical company focused on the development of novel, oral, small molecule therapies targeting STAT3 to treat inflammatory and proliferative diseases with significant unmet need. STAT3 is a central mediator across critical signaling pathways that drive uncontrolled proliferation, survival and immune dysregulation. STAT3 is also positioned at the intersection of many signaling pathways integral to the survival and immune evasion of cancer cells. The Company is conducting clinical trials with TTI-109 in healthy volunteers and TTI-101 in hepatocellular carcinoma (NCT05440708). To learn more, please visit tvarditherapeutics.com or follow us on LinkedIn and X (Twitter).

Current securities

Recent company filings

  1. 10-Q filingAug 14, 2026
  2. Results of Operations and Financial ConditionAug 14, 2026
  3. Regulation FD DisclosureJul 30, 2026
  4. Other EventsJul 17, 2026
  5. 424B5 filingJul 17, 2026

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