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BCS

Changes in Beneficial Ownership · 4

Castle Biosciences, Inc.

CSTLNASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Oct 7, 2026Accepted Oct 7, 2026, 4:10 PM EDTFiling CIK 1447362Accession 0001628280-26-065327
Share

Structured filing — 4

wk-form4_1791403842.xml

Open full document ↗

Filing details

Report period
2026-10-05
Issuer
CASTLE BIOSCIENCES INC
Issuer CIK
0001447362
Trading symbol
CSTL
Rule 10b5-1 indication
Checked

Reporting owner 1

Name
MAETZOLD DEREK J
Reporting owner CIK
0001239501
Relationship
Director · Officer
Officer title
Pres. & Chief Exec. Officer
Address
C/O CASTLE BIOSCIENCES, INC., 1500 W. PARKWOOD AVE SUITE 400, FRIENDSWOOD, TX, 77546

Non-derivative transactions

Non-derivative transactions · 4 reported rows
SecurityTransaction dateCodeAmountA / DPrice (USD)Owned afterOwnershipNature of ownership
Common Stock2026-10-05M · Form 4[F1]8,165A2.3929,644D
Common Stock2026-10-05S · Form 4[F1]8,580D35.566[F2]21,064D
Common Stock2026-10-05S · Form 4[F1]3,198D35.566[F2]8,038IBy The Maetzold Descendants 2020 Trust[F3]
Common Stock2026-10-05S · Form 4[F1]2,718D35.566[F2]6,832IBy Derek Maetzold 2020 Irrevocable Trust[F4]
Table key
M · Form 4
Exempt derivative exercise or conversion under Rule 16b-3
A
Acquired
D
Disposed
S · Form 4
Sale on the market or privately
I
Indirect

Non-derivative holdings

Non-derivative holdings · 8 reported rows
SecurityAmount ownedOwnershipNature of ownership
Common Stock11,256IBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk[F5]
Common Stock11,256IBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold[F6]
Common Stock11,256IBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold[F7]
Common Stock11,256IBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold[F8]
Common Stock11,963IBy DJM Grantor Retained Annuity Trust No. 6[F9]
Common Stock27,862IBy DJM Grantor Retained Annuity Trust No. 7[F10]
Common Stock40,935IBy DJM Grantor Retained Annuity Trust No. 8[F11]
Common Stock23,216IDJM Grantor Retained Annuity Trust No. 9[F12]
Table key
I
Indirect

Derivative transactions

Derivative transactions · 1 reported row
SecurityConversion / exercise price (USD)Transaction dateCodeAmountA / DPrice (USD)ExercisableExpiresUnderlying securityUnderlying sharesOwned afterOwnership
Stock option (right to buy)2.392026-10-05M · Form 4[F1]8,165D0[F13]2028-05-09Common Stock8,1650D
Table key
M · Form 4
Exempt derivative exercise or conversion under Rule 16b-3
D
Direct

Footnotes

F1
These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026.↩ 1↩ 2↩ 3↩ 4↩ 5
F2
This transaction was executed in multiple trades at prices ranging from $35.310 to $35.965, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.↩ 1↩ 2↩ 3
F3
Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.↩ 1
F4
Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.↩ 1
F5
Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.↩ 1
F6
Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.↩ 1
F7
Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.↩ 1
F8
Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.↩ 1
F9
Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.↩ 1
F10
Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.↩ 1
F11
Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.↩ 1
F12
Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.↩ 1
F13
The shares subject to the option are fully vested.↩ 1

Signature 1

Signed
/s/ Frank Stokes, Attorney-in-fact
Date
2026-10-07

Company context

Current securities

Recent company filings

  1. SCHEDULE 13G/A - filed by PRINCIPAL GLOBAL INVESTORS regarding CASTLE BIOSCIENCES INCOct 29, 2026
  2. 4 filingOct 21, 2026
  3. 144 filingOct 5, 2026
  4. 4 filingSep 23, 2026
  5. 4 filingSep 15, 2026

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