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Notice of Proposed Sale · 144

X4 Pharmaceuticals, Inc.

XFORNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Oct 1, 2026Accepted Oct 1, 2026, 8:05 PM EDTFiling CIK 1501697Accession 0001276750-26-000008
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Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
X4 Pharmaceuticals, Inc
Issuer CIK
0001501697
SEC file number
001-38295
Phone
508-633-4447
Person for whose account securities are to be sold
David Kirske
Relationships to issuer
Officer
Street
61 NORTH BEACON STREET
Street (continued)
4TH FLOOR
City
BOSTON
State / country code
MA
Postal code
02134

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Common Stock11,76733,658.4799,146,74310/01/2026NASDAQMorgan Stanley Smith Barney LLC

Broker / market maker — proposed row 1, entry 1

Name
Morgan Stanley Smith Barney LLC
Street
New York Plaza, 38th Floor
City
New York
State / country code
NY
Postal code
10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Common Stock09/30/2026Restricted Stock Unit VestingIssuer32,209N09/30/2026Compensation

Prior-sale reporting

Nothing to report for the preceding three months
Y

Remarks

Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

Notice signature

Notice date
10/01/2026
Signed
/s/ Mitch Buckley as attorney-in-fact for David Kirske

Company context

X4 is delivering progress for patients by developing and commercializing innovative therapies for those with rare hematology diseases and significant unmet needs. Leveraging expertise in CXCR4, X4 has successfully developed mavorixafor, an orally available CXCR4 antagonist that is currently being marketed in the U.S. as XOLREMDI® in its first indication. The company is also evaluating additional uses of mavorixafor and is conducting a global, pivotal Phase 3 clinical trial (4WARD) in people with certain

Current securities

Historical securities (2)

Recent company filings

  1. Other EventsSep 9, 2026
  2. Other EventsSep 8, 2026
  3. SCHEDULE 13G/A - filed by Deep Track Capital, LP regarding X4 Pharmaceuticals, IncAug 14, 2026
  4. 4 filingAug 13, 2026
  5. 4 filingAug 13, 2026

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