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BCS

Notice of Proposed Sale · 144

Wave Life Sciences, Inc.

WVENASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Aug 12, 2026Accepted Aug 12, 2026, 4:32 PM EDTFiling CIK 1555851Accession 0001950047-26-008025
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Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
WAVE LIFE SCIENCES INC
Issuer CIK
0001631574
SEC file number
001-37627
Phone
617-949-2900
Person for whose account securities are to be sold
ADRIAN G RAWCLIFFE
Relationships to issuer
Director
Street
733 Concord Avenue
City
Cambridge
State / country code
X1
Postal code
02138

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Common12,70064,071.50197,048,17508/12/2026NASDAQMorgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name
Morgan Stanley Smith Barney LLC Executive Financial Services
Street
1 New York Plaza
Street (continued)
8th Floor
City
New York
State / country code
NY
Postal code
10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Common08/11/2026Restricted Stock UnitsIssuer12,700N08/11/2026N/A

Prior-sale reporting

Nothing to report for the preceding three months
Y

Notice signature

Notice date
08/12/2026
Signed
/s/ Adrian G Rawcliffe
Plan adoption dates
03/06/2026

Company context

Wave Life Sciences (Nasdaq: WVE) is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Wave’s PRISM® platform combines multiple modalities, chemistry innovation, and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and common disorders. Its toolkit of RNA-targeting modalities, including RNAi (SpiNA) and RNA editing (AIMers), provides Wave with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Wave’s lead pipeline programs include obesity (WVE-007), alpha-1 antitrypsin deficiency (WVE-006), and PNPLA3 I148M liver disease (WVE-008), as well as several preclinical programs utilizing the company’s versatile RNA medicines platform. Driven by the calling to “Reimagine Possible,” Wave is leading the charge toward a world in which human potential is no longer hindered by the burden of disease. Wave is headquartered in Cambridge, MA. For more information on Wave’s science, pipeline and people, please visit www.wavelifesciences.com and follow Wave on X and LinkedIn.

Current securities

Recent company filings

  1. 10-Q filingOct 27, 2026
  2. Results of Operations and Financial ConditionOct 27, 2026
  3. ARS filingOct 14, 2026
  4. DEF 14A filingOct 14, 2026
  5. 4 filingOct 7, 2026

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