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BCS

Changes in Beneficial Ownership · 4

Axsome Therapeutics, Inc.

AXSMNASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Jul 1, 2026Accepted Jul 1, 2026, 7:30 PM EDTFiling CIK 1579428Accession 0001193125-26-292985
Share

Structured filing — 4

ownership.xml

Open full document ↗

Filing details

Report period
2026-07-01
Issuer
Axsome Therapeutics, Inc.
Issuer CIK
0001579428
Trading symbol
AXSM
Rule 10b5-1 indication
Checked

Reporting owner 1

Name
TABUTEAU HERRIOT
Reporting owner CIK
0001219927
Relationship
Director · Officer · 10% owner
Officer title
Chief Executive Officer
Address
C/O AXSOME THERAPEUTICS, INC., ONE WORLD TRADE CENTER, 29TH FLOOR, NEW YORK, NY, 10007

Non-derivative transactions

Non-derivative transactions · 2 reported rows
SecurityTransaction dateCodeAmountA / DPrice (USD)Owned afterOwnership
Common Stock2026-07-01M · Form 4[F1][F2]49,666A4.9556,895D
Common Stock2026-07-01S · Form 4[F2][F3]49,666D240.25[F4]7,229D
Table key
M · Form 4
Exempt derivative exercise or conversion under Rule 16b-3
A
Acquired
D
Direct
S · Form 4
Sale on the market or privately

Non-derivative holdings

Non-derivative holdings · 1 reported row
SecurityAmount ownedOwnershipNature of ownership
Common Stock7,344,500ISee Footnote[F5]
Table key
I
Indirect

Derivative transactions

Derivative transactions · 1 reported row
SecurityConversion / exercise price (USD)Transaction dateCodeAmountA / DPrice (USD)ExercisableExpiresUnderlying securityUnderlying sharesOwned afterOwnership
Stock Option (Right to Buy)240.252026-07-01M · Form 4[F1][F2]49,666D0.002018-03-152027-03-15Common Stock49,66649,664D
Table key
M · Form 4
Exempt derivative exercise or conversion under Rule 16b-3
D
Direct

Footnotes

F1
Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.↩ 1↩ 2
F2
Such transaction was pursuant to a pre-approved 10b5-1 plan.↩ 1↩ 2↩ 3
F3
Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.↩ 1
F4
Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $237.64 and $244.71.↩ 1
F5
Such shares are held by an entity, of which the reporting person has voting and dispositive power, and therefore, the reporting person is deemed to be the indirect beneficial owner of such shares.↩ 1

Signature 1

Signed
/s/ Nick Pizzie, Attorney-in-Fact
Date
2026-07-01

Company context

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, agitation associated with dementia due to Alzheimer’s disease, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, as well as multiple novel product candidates addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

Current securities

Recent company filings

  1. 10-Q filingNov 2, 2026
  2. Results of Operations and Financial Condition · Other EventsNov 2, 2026
  3. 10-Q filingAug 10, 2026
  4. Results of Operations and Financial Condition · Other EventsAug 10, 2026
  5. 4 filingAug 7, 2026

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