Notice of Proposed Sale · 144

Natera, Inc.

NTRANASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Sep 23, 2026Accepted Sep 23, 2026, 10:58 AM EDTFiling CIK 1604821Accession 0001949846-26-000594

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Structured filing — 144

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer: Natera, Inc.
Issuer CIK: 0001604821
SEC file number: 001-37478
Phone: 650-249-9090
Person for whose account securities are to be sold: Sheena Jonathan
Relationships to issuer: Director
Street: 13011 MCCALLEN PASS
Street (continued): BUILDING A SUITE 100
City: AUSTIN
State / country code: TX
Postal code: 78753

Securities proposed for sale

Securities proposed for sale · 1 reported row
Security	Proposed units	Aggregate market value	Units outstanding	Approximate sale date	Exchange	Broker / market maker
Common	21,064	8,163,402.00	144,144,170	09/23/2026	NASDAQ	Charles Schwab & Co., Inc.

Broker / market maker — proposed row 1, entry 1

Name: Charles Schwab & Co., Inc.
Street: 3000 Schwab Way
City: Westlake
State / country code: TX
Postal code: 76262

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
Security	Acquired	Nature of acquisition	Acquired from	Amount acquired	Gift transaction	Payment date	Nature of payment
COMMON	04/30/2012	FOUNDERS SHARES	ISSUER	21,064	N	04/30/2012	NA

Sales reported in the preceding three months

Sales reported in the preceding three months · 9 reported rows
Seller	Security	Sale date	Amount sold	Gross proceeds
Jonathan Sheena	COMMON	07/13/2026	3,150	836,898.00
JONATHAN SHEENA	COMMON	07/15/2026	1,500	410,825.00
JONATHAN SHEENA C/O	COMMON	08/07/2026	9,150	2,888,325.00
JONATHAN SHEENA	COMMON	08/10/2026	6,000	1,951,942.00
JONATHAN SHEENA	COMMON	09/15/2026	6,000	2,100,430.00
JONATHAN SHEENA	COMMON	09/16/2026	3,150	1,115,713.00
JONATHAN SHEENA	COMMON	07/27/2026	288	75,021.00
JONATHAN SHEENA	COMMON	07/28/2026	191	48,527.00
JONATHAN SHEENA	COMMON	08/03/2026	109	29,210.00

Seller — prior-sale row 1, entry 1

Name: Jonathan Sheena
Street: C/O 13011 McCallen Pass,
Street (continued): Building A Suit 100
City: Austin
State / country code: TX
Postal code: 78753

Seller — prior-sale row 2, entry 1

Name: JONATHAN SHEENA
Street: C/O 13011 McCallen Pass
Street (continued): Building A Suite 100
City: Austin
State / country code: TX
Postal code: 78753

Seller — prior-sale row 3, entry 1

Name: JONATHAN SHEENA C/O
Street: 13011 McCallen Pass
Street (continued): Building A Suite 100
City: Austin
State / country code: TX
Postal code: 78753

Seller — prior-sale row 4, entry 1

Name: JONATHAN SHEENA
Street: C/O 13011 McCallen Pass
Street (continued): Building A Suite 100
City: Austin
State / country code: TX
Postal code: 78753

Seller — prior-sale row 5, entry 1

Name: JONATHAN SHEENA
Street: C/O 13011 McCallen Pass
Street (continued): Building A Suite 100
City: Austin
State / country code: TX
Postal code: 78753

Seller — prior-sale row 6, entry 1

Name: JONATHAN SHEENA
Street: C/O 13011 McCallen Pass
Street (continued): Building A Suite 100
City: Austin
State / country code: TX
Postal code: 78753

Seller — prior-sale row 7, entry 1

Name: JONATHAN SHEENA
Street: C/O 13011 McCallen Pass
Street (continued): Building A Suite 100
City: Austin
State / country code: TX
Postal code: 78753

Seller — prior-sale row 8, entry 1

Name: JONATHAN SHEENA
Street: C/O 13011 McCallen Pass
Street (continued): Building A Suite 100
City: Austin
State / country code: TX
Postal code: 78753

Seller — prior-sale row 9, entry 1

Name: JONATHAN SHEENA
Street: C/O 13011 McCallen Pass
Street (continued): Building A Suite 100
City: Austin
State / country code: TX
Postal code: 78753

Prior-sale reporting

Nothing to report for the preceding three months: N

Remarks

FULL ACCOUNT TITLES: CARALUNA 1 TRUST, CARALUNA 1 LLC and CARALUNA 2 TRUST, CARALUNA 2 LLC

Notice signature

Notice date: 09/23/2026
Signed: Jonathan Sheena
Plan adoption dates: 06/11/2026

Company context

Natera™ is a global leader in cell-free DNA and precision medicine, dedicated to oncology, women’s health, and organ health. We aim to make personalized genetic testing and diagnostics part of the standard-of-care to protect health and inform earlier, more targeted interventions that help lead to longer, healthier lives. Natera’s tests are supported by more than 400 peer-reviewed publications that demonstrate excellent performance. Natera operates ISO 13485-certified and CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in Austin, Texas, and San Carlos, California, and through Foresight Diagnostics, its subsidiary, operates an ISO 27001-certified and CAP-accredited laboratory certified under CLIA in Boulder, Colorado. For more information, visit www.natera.com.

Current securities

NTRANASDAQ · EQUITY · Current

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