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BCS

Changes in Beneficial Ownership · 4

Rhythm Pharmaceuticals, Inc.

RYTMNASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Sep 14, 2026Accepted Sep 14, 2026, 7:37 PM EDTFiling CIK 1649904Accession 0001649904-26-000026
Share

Structured filing — 4

form4.xml

Open full document ↗

Filing details

Report period
2026-09-14
Issuer
RHYTHM PHARMACEUTICALS, INC.
Issuer CIK
0001649904
Trading symbol
RYTM
Rule 10b5-1 indication
Checked

Reporting owner 1

Name
Meeker David P
Reporting owner CIK
0001385155
Relationship
Director · Officer
Officer title
President and CEO
Address
C/O RHYTHM PHARMACEUTICALS, INC., 222 BERKELEY STREET, 12TH FLOOR, BOSTON, MA, 02116

Non-derivative transactions

Non-derivative transactions · 6 reported rows
SecurityTransaction dateCodeAmountA / DPrice (USD)Owned afterOwnership
Common Stock2026-09-14M · Form 4[F1]50,000A6.05289,258[F2]D
Common Stock2026-09-14S · Form 4[F1]6,439D101.7464[F3]282,819D
Common Stock2026-09-14S · Form 4[F1]30,746D102.347[F4]252,073D
Common Stock2026-09-14S · Form 4[F1]8,698D103.43[F5]243,375D
Common Stock2026-09-14S · Form 4[F1]1,817D104.5487[F6]241,558D
Common Stock2026-09-14S · Form 4[F1]2,300D105.19[F7]239,258D
Table key
M · Form 4
Exempt derivative exercise or conversion under Rule 16b-3
A
Acquired
D
Direct
S · Form 4
Sale on the market or privately

Derivative transactions

Derivative transactions · 1 reported row
SecurityConversion / exercise price (USD)Transaction dateCodeAmountA / DPrice (USD)ExercisableExpiresUnderlying securityUnderlying sharesOwned afterOwnership
Employee Stock Option (Right to Buy)6.052026-09-14M · Form 450,000D0[F8]2027-02-07Common Stock50,00015,431D
Table key
M · Form 4
Exempt derivative exercise or conversion under Rule 16b-3
D
Direct

Footnotes

F1
The exercise and sales reported in this form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 15, 2026.↩ 1↩ 2↩ 3↩ 4↩ 5↩ 6
F2
Includes 242 shares acquired under the Rhythm Pharmaceuticals, Inc. employee stock purchase plan on 2-28-2026.↩ 1
F3
The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $100.96 to $101.95 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1
F4
The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $101.96 to $102.94 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1
F5
The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $102.97 to $103.96 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1
F6
The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $103.97 to $104.94 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1
F7
The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $105.00 to $105.31 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1
F8
The stock options were granted on February 8, 2017 and vested and became exercisable in three equal annual installments measured from January 6, 2017.↩ 1

Signature 1

Signed
/s/ Stephen Vander Stoep, attorney-in-fact for David P. Meeker
Date
2026-09-14

Company context

Current securities

Recent company filings

  1. SCHEDULE 13G - filed by JPMORGAN CHASE & CO regarding RHYTHM PHARMACEUTICALS, INC.Oct 13, 2026
  2. 4 filingSep 1, 2026
  3. 144 filingAug 13, 2026
  4. 144 filingAug 12, 2026
  5. 10-Q filingAug 4, 2026

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