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BCS

Notice of Proposed Sale · 144

Alector, Inc.

ALECNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Sep 1, 2026Accepted Sep 1, 2026, 8:00 PM EDTFiling CIK 1653087Accession 0001193125-26-379020
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Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
Alector, Inc.
Issuer CIK
0001653087
SEC file number
001-38792
Phone
(415)-231-5660
Person for whose account securities are to be sold
Neil L. Berkley
Relationships to issuer
Officer
Street
131 Oyster Point Blvd.
Street (continued)
Suite 600
City
South San Francisco
State / country code
CA
Postal code
94080

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Common Stock32,10377,047.20111,692,01109/02/2026NasdaqMorgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name
Morgan Stanley Smith Barney LLC Executive Financial Services
Street
1 New York Plaza
Street (continued)
8th Floor
City
New York
State / country code
NY
Postal code
10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Common Stock09/01/2026Vesting of Restricted Stock UnitsIssuer63,095N09/01/2026(1)

Sales reported in the preceding three months

Sales reported in the preceding three months · 1 reported row
SellerSecuritySale dateAmount soldGross proceeds
Neil BerkleyCommon Stock06/02/202619,36038,221.16

Seller — prior-sale row 1, entry 1

Name
Neil Berkley
Street
C/O Alector, Inc.
Street (continued)
131 Oyster Point Blvd., Suite 600
City
South San Francisco
State / country code
CA
Postal code
94080

Prior-sale reporting

Nothing to report for the preceding three months
N

Remarks

(1) The securities to be sold were received upon the settlement of vested restricted stock units, or RSUs. The reported shares will be sold to satisfy the reporting person's tax obligations in connection with the vesting of RSUs.

Notice signature

Notice date
09/01/2026
Signed
/s/ Grace Wong-Sarad, by power of attorney

Company context

Alector is a biotechnology company focused on developing therapies to counteract the devastating progression of neurodegenerative diseases. Leveraging the principles of genetics, immunology, and neuroscience, the company is advancing a portfolio of programs that aim to remove toxic proteins, replace missing proteins, and restore immune and nerve cell function. Supported by biomarkers, Alector’s product candidates seek to treat a range of indications, such as Alzheimer’s disease and Parkinson's disease. The company is also developing Alector Brain Carrier (ABC), a proprietary blood-brain barrier platform, which is being applied to its preclinical and research pipeline. ABC aims to enhance the delivery of therapeutics, achieve deeper brain penetration and efficacy at lower doses, and ultimately improve patient outcomes while reducing costs. Alector is headquartered in South San Francisco, California. For more information, please visit www.alector.com.

Current securities

Recent company filings

  1. Entry into a Material Definitive Agreement · Results of Operations and Financial Condition · Regulation FD Disclosure · Other EventsOct 5, 2026
  2. 144 filingSep 4, 2026
  3. 144 filingSep 2, 2026
  4. 144 filingSep 1, 2026
  5. 10-Q filingAug 6, 2026

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