Changes in Beneficial Ownership · 4

Medpace Holdings, Inc.

MEDPNASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Sep 21, 2026Accepted Sep 21, 2026, 4:23 PM EDTFiling CIK 1668397Accession 0001622058-26-000014

wk-form4_1790022182.xml

Name: Troendle August J.
Reporting owner CIK: 0001622058
Relationship: Director · Officer · 10% owner
Officer title: President & CEO
Address: C/O MEDPACE HOLDINGS, INC., 5375 MEDPACE WAY, CINCINNATI, OH, 45227

Non-derivative transactions · 1 reported row
Security	Transaction date	Code	Amount	A / D	Price (USD)	Owned after	Ownership
Common Stock	2026-09-17	S · Form 4^[F1]	10,880	D	620.40^[F2]	504,273	D

Table key

Non-derivative holdings · 1 reported row
Security	Amount owned	Ownership	Nature of ownership
Common Stock	4,733,019	I	By Medpace Investors, LLC^[F3]

Table key

F1: The transactions reported on this Form 4 were effected pursuant to a limit order placed by the Reporting Person during an open window period.↩ 1
F2: The reported price is a weighted average price. These shares were sold in multiple transactions ranging from $620.00 to $622.21. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission upon request.↩ 1
F3: The Reporting Person is the sole manager and controlling unit holder of Medpace Investors, LLC ("MPI") and has sole voting and investment control with respect to the securities held by MPI. The Reporting Person may be deemed to indirectly beneficially own the securities of the Issuer held by MPI but disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.↩ 1