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BCS

Current Report · Items 5.02 · 8-K

Spero Therapeutics, Inc.

SPRONASDAQEQUITYCurrent

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers. (b) On October 26, 2026, Spero Therapeutics, Inc. (the “Company”) announced that Timothy Keutzer, the Company’s Chief Operating Officer, will retire from the Company effective as of December 31, 2026 (the “Effective Date”).…

Filed Oct 27, 2026Accepted Oct 27, 2026, 5:16 PM EDTCIK 1701108Accession 0001193125-26-434452
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Company context

Spero Therapeutics is a clinical-stage biopharmaceutical company focused on advancing next-generation medicines for patients with serious immune-mediated diseases. The company’s lead program, SP001, is a third-generation, Fc-silent anti-CD40L monoclonal antibody being advanced first in IgG4-related disease, with potential for development in additional immunological & inflammatory diseases. For more information, visit www.sperotx.com.

Current securities

Recent company filings

  1. S-8 filingOct 28, 2026
  2. EFFECT filingSep 10, 2026
  3. Entry into a Material Definitive Agreement · Other EventsAug 28, 2026
  4. S-3 filingAug 28, 2026
  5. Results of Operations and Financial ConditionAug 12, 2026

Registered securities in this filing

SPERO THERAPEUTICS, INC. · 8-K · Filed 2026-10-27

As filed in this accession. Current/historical status below comes from the governed listing record; the cover itself remains exact to this filing.

Common Stock, $0.001 par value

Symbol
SPRO
Exchange
NASDAQ
Classification
COMMON
Status
Current
Filing context

Context: duration_2026-10-26_to_2026-10-26

Dimensions: Not supplied

Accession 000119312526434452 · 1 registered-security cover member

Read the exact SEC filing ↗

Disclosure sections

Items 5.02

Select an item to read the extracted section. The as-filed document remains the primary evidence.

Item 5.02Item 5.02 - Departure/Election of Directors
Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers. (b)  On October 26, 2026, Spero Therapeutics, Inc. (the “Company”) announced that Timothy Keutzer, the Company’s Chief Operating Officer, will retire from the Company effective as of December 31, 2026 (the “Effective Date”). In connection with his retirement, the Company expects to enter into a consulting arrangement with Mr. Keutzer on or about the Effective Date, pursuant to which Mr. Keutzer will provide advisory services to the Company in support of the transition until approximately February 28, 2027, unless earlier terminated by either party on fifteen days’ prior written notice (the “Consulting Period”). Pursuant to the terms of the Consulting Agreement, Mr. Keutzer will be paid an hourly rate for his services during the Consulting Period. Mr. Keutzer’s retirement follows 11 years of dedicated service, leadership and significant contributions to the Company.

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