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BCS

Beneficial Ownership Report · SCHEDULE 13G/A

Tempus AI, Inc.

TEMNASDAQEQUITYCurrent

Beneficial Ownership Report

Filed Nov 6, 2026Accepted Nov 6, 2026, 2:28 PM ESTFiling CIK 1717115Accession 0001104659-26-123788
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Structured filing — SCHEDULE 13G/A

primary_doc.xml

Open full document ↗

Amendment · This filing reports the amendment as submitted.

Subject company

Company
Tempus AI, Inc.
Company CIK
0001717115
Street
600 West Chicago Avenue
Street (continued)
Suite 510
City
Chicago
State / country code
IL
Postal code
60654

Statement details

Amendment number
1
Security class
Common Stock
Event date
10/31/2026
Rule designation
Rule 13d-1(b)

Reporting person 1

Name
ARK Investment Management LLC
Citizenship / organization
DE
Reporting person type
IA
Aggregate amount owned
8,607,836.00
Percent of class
4.91
Sole voting power
8,161,270.00
Shared voting power
124,106.00
Sole dispositive power
8,607,836.00
Shared dispositive power
0.00
Aggregate excludes certain shares
N

Reporting person 2

Name
Catherine D. Wood
Citizenship / organization
X1
Reporting person type
HC · IN
Aggregate amount owned
8,607,836.00
Percent of class
4.91
Sole voting power
0.00
Shared voting power
8,285,376.00
Sole dispositive power
0.00
Shared dispositive power
8,607,836.00
Aggregate excludes certain shares
N

Item 1

Issuer

Tempus AI, Inc.

Principal executive office address

600 West Chicago Avenue, Suite 510, Chicago, IL 60654

Item 2

Citizenship

(i) ARK: Delaware (ii) Catherine D. Wood: United States

Filing person

(i) ARK Investment Management LLC ("ARK") (ii) Catherine D. Wood

Principal business or residence address

ARK and Catherine D. Wood: 200 Central Avenue, St. Petersburg, FL 33701

Item 3

Not applicable indication

N

Type of filing person

IA · HC

Item 4

Percent of class

ARK and Catherine D. Wood: 4.91

Amount beneficially owned

ARK and Catherine D. Wood: 8,607,836

Sole voting power

(i) ARK: 8,161,270 (ii) Catherine D. Wood: 0

Shared voting power

(i) ARK: 124,106 (ii) Catherine D. Wood: 8,285,376

Sole dispositive power

(i) ARK: 8,607,836 (ii) Catherine D. Wood: 0

Shared dispositive power

(i) ARK: 0 (ii) Catherine D. Wood: 8,607,836

Item 5

Not applicable indication

N

Ownership of 5% or less

Y

Item 6

Not applicable indication

Y

Item 7

Not applicable indication

Y

Item 8

Not applicable indication

Y

Item 9

Not applicable indication

Y

Item 10

Not applicable indication

N

Certifications

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

Signature 1

Reporting person
ARK Investment Management LLC
Signed
/s/ Kathleen Fontano
Title
Kathleen Fontano, Chief Compliance Officer
Date
11/06/2026

Signature 2

Reporting person
Catherine D. Wood
Signed
/s/ Catherine D. Wood
Title
Catherine D. Wood, Chief Executive Officer, Chief Investment Officer
Date
11/06/2026

Filed exhibits

Company context

Tempus is a technology company making precision medicine a reality through the practical application of artificial intelligence in healthcare. With one of the world’s largest libraries of de-identified multimodal data and an intelligent operating system that makes that data accessible and actionable, Tempus connects AI, diagnostics and clinical workflows to deliver more personalized patient care and accelerate the discovery, development and delivery of better medicines. By continuously transforming data into insights, Tempus

Current securities

Recent company filings

  1. 4 filingNov 4, 2026
  2. 10-Q filingNov 2, 2026
  3. Results of Operations and Financial Condition · Regulation FD DisclosureNov 2, 2026
  4. 4 filingOct 29, 2026
  5. SCHEDULE 13G/A - filed by KEYWELL BRADLEY A regarding Tempus AI, Inc.Oct 28, 2026

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