Notice of Proposed Sale · 144

Korsana Biosciences, Inc.

KRSANASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Oct 22, 2026Accepted Oct 22, 2026, 4:06 PM EDTFiling CIK 1755237Accession 0001950047-26-010364

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Structured filing — 144

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer: KORSANA BIOSCIENCES, INC.
Issuer CIK: 0001755237
SEC file number: 001-38787
Phone: (781) 516-2325
Person for whose account securities are to be sold: MICHAEL HIGGINS
Relationships to issuer: Director
Street: 203 Crescent Street,
Street (continued): Bldgs. #3/3A/4, Suite 503,
City: Waltham
State / country code: MA
Postal code: 02453

Securities proposed for sale

Securities proposed for sale · 1 reported row
Security	Proposed units	Aggregate market value	Units outstanding	Approximate sale date	Exchange	Broker / market maker
Common	1,107	35,424.00	45,541,424	10/22/2026	NASDAQ	Morgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name: Morgan Stanley Smith Barney LLC Executive Financial Services
Street: 1 New York Plaza
Street (continued): 8th Floor
City: New York
State / country code: NY
Postal code: 10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
Security	Acquired	Nature of acquisition	Acquired from	Amount acquired	Gift transaction	Payment date	Nature of payment
Common	11/30/2023	Restricted Stock	Issuer	1,107	N	11/30/2023	Not Applicable

Sales reported in the preceding three months

Sales reported in the preceding three months · 2 reported rows
Seller	Security	Sale date	Amount sold	Gross proceeds
MICHAEL HIGGINS	Common	09/18/2026	1,001	33,033.00
MICHAEL HIGGINS	Common	09/17/2026	235	7,599.71

Seller — prior-sale row 1, entry 1

Name: MICHAEL HIGGINS
Street: 203 Crescent Street,
Street (continued): Bldgs. #3/3A/4, Suite 503,
City: Waltham
State / country code: MA
Postal code: 02453

Seller — prior-sale row 2, entry 1

Name: MICHAEL HIGGINS
Street: 203 Crescent Street,
Street (continued): Bldgs. #3/3A/4, Suite 503,
City: Waltham
State / country code: MA
Postal code: 02453

Prior-sale reporting

Nothing to report for the preceding three months: N

Remarks

The securities to be sold were acquired upon the vesting of restricted stock during the period of 11/30/2023 through 06/01/2026.

Notice signature

Notice date: 10/22/2026
Signed: /s/ Michael J Higgins

Company context

Korsana Biosciences is committed to building best-in-class therapeutics with the goal of reducing the burden of neurodegenerative diseases for patients and caregivers. The Company’s lead program, KRSA-028, is a next-generation shuttled antibody targeting amyloid beta for the treatment of Alzheimer’s disease. KRSA-028 leverages Therapeutic Targeting (THETA™), a novel CNS shuttle technology developed in partnership with Paragon Therapeutics and designed to enable dramatically higher drug concentrations in the brain and overcome the limitations of earlier shuttle technologies. In addition, Korsana is advancing a pipeline of innovative therapies for neurodegenerative diseases. For more information, please visit www.korsana.com and follow the Company on LinkedIn.

Current securities

KRSANASDAQ · EQUITY · Current

Historical securities (1)

CYCNNASDAQ · EQUITY · Historical · closed Sep 8, 2026

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