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Notice of Proposed Sale · 144

Ironwood Pharmaceuticals, Inc.

IRWDNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Sep 23, 2026Accepted Sep 23, 2026, 4:08 PM EDTFiling CIK 1808509Accession 0001808509-26-000003
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Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
IRONWOOD PHARMACEUTICALS INC
Issuer CIK
0001446847
SEC file number
001-34620
Phone
617-621-7722
Person for whose account securities are to be sold
Shetzline Michael
Relationships to issuer
Former Officer
Street
100 SUMMER STREET, SUITE 2300
City
BOSTON
State / country code
MA
Postal code
02110

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Class A Common Stock83,306377,376.18165,239,94709/24/2026NasdaqE Trade Securities LLC

Broker / market maker — proposed row 1, entry 1

Name
E Trade Securities LLC
Street
3 Edison Drive
City
Alpharetta
State / country code
GA
Postal code
30005

Acquisition of securities to be sold

Acquisition of securities to be sold · 7 reported rows
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Class A Common Stock03/08/2023Restricted Stock Unit award granted pursuant to the Issuer's 2019 Equity Incentive PlanIronwood Pharmaceuticals, Inc.17,467N03/08/2023N/A
Class A Common Stock02/12/2024Restricted Stock Unit award granted pursuant to the Issuer's Amended and Restated 2019 Equity Incentive PlanIronwood Pharmaceuticals, Inc.13,606N02/12/2024N/A
Class A Common Stock02/12/2024Restricted Stock Unit award granted pursuant to the Issuer's Amended and Restated 2019 Equity Incentive PlanIronwood Pharmaceuticals, Inc.12,447N02/12/2024N/A
Class A Common Stock02/10/2025Restricted Stock Unit award granted pursuant to the Issuer's Amended and Restated 2019 Equity Incentive PlanIronwood Pharmaceuticals, Inc.33,333N02/10/2025N/A
Class A Common Stock02/10/2025Restricted Stock Unit award granted pursuant to the Issuer's Amended and Restated 2019 Equity Incentive PlanIronwood Pharmaceuticals, Inc.30,494N02/10/2025N/A
Class A Common Stock03/10/2026Restricted Stock Unit award granted pursuant to the Issuer's Amended and Restated 2019 Equity Incentive PlanIronwood Pharmaceuticals, Inc.34,153N03/10/2026N/A
Class A Common Stock03/10/2026Restricted Stock Unit award granted pursuant to the Issuer's Amended and Restated 2019 Equity Incentive PlanIronwood Pharmaceuticals, Inc.31,244N03/10/2026N/A

Prior-sale reporting

Nothing to report for the preceding three months
Y

Remarks

Shares sold to cover taxes from the vesting of stock awards granted by the Issuer.

Notice signature

Notice date
09/23/2026
Signed
/s/ Michael Shetzline

Company context

Ironwood Pharmaceuticals (Nasdaq: IRWD) is a biotechnology company developing and commercializing life-changing therapies for people living with gastrointestinal (GI) and rare diseases. Ironwood is advancing apraglutide, a next-generation, long-acting synthetic GLP-2 analog being developed for short bowel syndrome patients who are dependent on parenteral support. In addition, Ironwood has been a pioneer in the development of LINZESS® (linaclotide), the U.S. branded prescription market leader for the treatment of irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC). Building upon our history of innovation, we keep patients at the heart of our R&D and commercialization efforts to reduce the burden of diseases and address significant unmet needs.

Current securities

Recent company filings

  1. 4 filingSep 17, 2026
  2. SCHEDULE 13G/A - filed by ARMISTICE CAPITAL, LLC regarding IRONWOOD PHARMACEUTICALS INCAug 14, 2026
  3. 10-Q filingAug 6, 2026
  4. Results of Operations and Financial ConditionAug 6, 2026
  5. 144 filingJul 7, 2026

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