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Notice of Proposed Sale · 144

Nurix Therapeutics, Inc.

NRIXNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Oct 2, 2026Accepted Oct 2, 2026, 4:19 PM EDTFiling CIK 1817199Accession 0001950047-26-010001
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Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
NURIX THERAPEUTICS INC
Issuer CIK
0001549595
SEC file number
001-39398
Phone
4156605320
Person for whose account securities are to be sold
CHRISTINE RING
Relationships to issuer
Officer
Street
1600 Sierra Point Parkway
City
Brisbane
State / country code
CA
Postal code
94005

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Common5,786135,045.24103,781,68310/02/2026NASDAQMorgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name
Morgan Stanley Smith Barney LLC Executive Financial Services
Street
1 New York Plaza
Street (continued)
8th Floor
City
New York
State / country code
NY
Postal code
10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Common10/02/2026Exercise of Stock OptionsIssuer5,786N10/02/2026Cash

Sales reported in the preceding three months

Sales reported in the preceding three months · 4 reported rows
SellerSecuritySale dateAmount soldGross proceeds
10b5-1 Sales for CHRISTINE RINGCommon09/02/20265,787149,072.54
10b5-1 Sales for CHRISTINE RINGCommon08/03/20265,787133,367.20
10b5-1 Sales for CHRISTINE RINGCommon08/03/202610,802248,991.54
CHRISTINE RINGCommon07/30/20263,84789,953.63

Seller — prior-sale row 1, entry 1

Name
10b5-1 Sales for CHRISTINE RING
Street
1600 Sierra Point Parkway
City
Brisbane
State / country code
CA
Postal code
94005

Seller — prior-sale row 2, entry 1

Name
10b5-1 Sales for CHRISTINE RING
Street
1600 Sierra Point Parkway
City
Brisbane
State / country code
CA
Postal code
94005

Seller — prior-sale row 3, entry 1

Name
10b5-1 Sales for CHRISTINE RING
Street
1600 Sierra Point Parkway
City
Brisbane
State / country code
CA
Postal code
94005

Seller — prior-sale row 4, entry 1

Name
CHRISTINE RING
Street
1600 Sierra Point Parkway
City
Brisbane
State / country code
CA
Postal code
94005

Prior-sale reporting

Nothing to report for the preceding three months
N

Notice signature

Notice date
10/02/2026
Signed
/s/ Christine Ring
Plan adoption dates
11/10/2025

Company context

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and autoimmune diseases. Nurix’s wholly owned, clinical stage pipeline includes degraders of Bruton’s tyrosine kinase (BTK), a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene B (CBL-B), an E3 ligase that regulates activation of multiple immune cell types including T cells and NK cells. Nurix also is advancing multiple potentially first-in-class or best-in-class degraders and degrader antibody conjugates (DACs) in its preclinical pipeline. Nurix’s partnered drug discovery pipeline consists of a preclinical stage degrader of STAT6, SAR448272/NX-3911, in collaboration with Sanofi, a clinical stage degrader of IRAK4, GS6791, in collaboration with Gilead, as well as multiple additional programs under collaboration agreements with Gilead Sciences, Inc., Sanofi S.A. and Pfizer Inc., within which Nurix retains certain options for co-development, co-commercialization and profit sharing in the United States for multiple drug candidates. Powered by an AI-integrated discovery engine capable of tackling virtually any protein class, and coupled with unparalleled ligase expertise, Nurix is headquartered in Brisbane, California. For additional information visit http://www.nurixtx.com.

Current securities

Recent company filings

  1. SCHEDULE 13G/A - filed by Vestal Point Capital, LP regarding Nurix Therapeutics, Inc.Aug 14, 2026
  2. SCHEDULE 13G/A - filed by Deep Track Capital, LP regarding Nurix Therapeutics, Inc.Aug 14, 2026
  3. SCHEDULE 13G filingJul 31, 2026
  4. 10-Q filingJul 9, 2026
  5. Results of Operations and Financial ConditionJul 9, 2026

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