Beneficial Ownership Report · SCHEDULE 13G/A
Clene Inc.
CLNNNASDAQEQUITYCurrent
Beneficial Ownership Report
Structured filing — SCHEDULE 13G/A
primary_doc.xml
Amendment · This filing reports the amendment as submitted.
Subject company
- Company
- Clene Inc.
- Company CIK
- 0001822791
- Street
- 6550 South Millrock Drive, Suite G50
- City
- Salt Lake City
- State / country code
- UT
- Postal code
- 84121
Statement details
- Amendment number
- 1
- Security class
- Common Stock, $0.0001 par value per share
- Event date
- 09/30/2026
- Rule designation
- Rule 13d-1(b)
Reporting person 1
- Name
- Empery Asset Management, LP
- Citizenship / organization
- DE
- Reporting person type
- IA · PN
- Aggregate amount owned
- 221,660.00
- Percent of class
- 1.56
- Sole voting power
- 0.00
- Shared voting power
- 221,660.00
- Sole dispositive power
- 0.00
- Shared dispositive power
- 221,660.00
- Aggregate excludes certain shares
- N
Reporting person 2
- Name
- Ryan M. Lane
- Citizenship / organization
- X1
- Reporting person type
- HC · IN
- Aggregate amount owned
- 221,660.00
- Percent of class
- 1.56
- Sole voting power
- 0.00
- Shared voting power
- 221,660.00
- Sole dispositive power
- 0.00
- Shared dispositive power
- 221,660.00
- Aggregate excludes certain shares
- N
Item 1
Issuer
Clene Inc.
Principal executive office address
6550 South Millrock Drive, Suite G50, Salt Lake City, UT 84121
Item 2
Citizenship
Citizenship is set forth in Row 4 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.
Filing person
This statement is filed by the entities and persons listed below, who are collectively referred to herein as "Reporting Persons," with respect to Common Stock, $0.0001 par value per share (the "Common Stock") of Clene Inc., a Delaware corporation (the "Company"): (i) Empery Asset Management, LP (the "Investment Manager"), with respect to the Common Stock held by funds to which the Investment Manager serves as investment manager (the "Empery Funds"); and (ii) Mr. Ryan M. Lane ("Mr. Lane"), with respect to the Common Stock held by the Empery Funds. The Investment Manager serves as the investment manager to each of the Empery Funds. Mr. Lane (the "Reporting Individual") is the managing member of a limited liability company that is the managing member of Empery AM GP, LLC (the "General Partner"), the general partner of the Investment Manager.
Principal business or residence address
The address of the business office of each of the Reporting Persons is: 1 Rockefeller Plaza, Suite 1205 New York, New York 10020
Item 3
Not applicable indication
N
Type of filing person
IA · HC
Item 4
Percent of class
1.56
Amount beneficially owned
The information required by Item 4(a) is set forth in Row 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The percentage set forth in this Schedule 13G is calculated based upon an aggregate of 14,213,981 shares of Common Stock outstanding as of September 15, 2026, as reported in the Company's Prospectus Supplement filed with the Securities and Exchange Commission pursuant to Rule 424(b)(5) on September 16, 2026. The Investment Manager, which serves as the investment manager to the Empery Funds, may be deemed to be the beneficial owner of all of the shares of Common Stock held by the Empery Funds. The Reporting Individual, as the managing member of a limited liability company that is the managing member of the General Partner of the Investment Manager with the power to exercise investment discretion, may be deemed to be the beneficial owner of all of the shares of Common Stock held by the Empery Funds. The foregoing should not be construed in and of itself as an admission by any Reporting Person as to beneficial ownership of the shares of Common Stock owned by another Reporting Person. Each of the Empery Funds and the Reporting Individual hereby disclaims any beneficial ownership of any such Common Stock.
Sole voting power
The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
Shared voting power
The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
Sole dispositive power
The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
Shared dispositive power
The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
Item 5
Not applicable indication
N
Ownership of 5% or less
Y
Item 6
Not applicable indication
Y
Item 7
Not applicable indication
Y
Item 8
Not applicable indication
Y
Item 9
Not applicable indication
Y
Item 10
Not applicable indication
N
Certifications
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
Signature 1
- Reporting person
- Empery Asset Management, LP
- Signed
- /s/ Ryan M. Lane
- Title
- Ryan M. Lane, Authorized Signatory
- Date
- 10/13/2026
Signature 2
- Reporting person
- Ryan M. Lane
- Signed
- /s/ Ryan M. Lane
- Title
- Ryan M. Lane, individually
- Date
- 10/13/2026