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BCS

Beneficial Ownership Report · SCHEDULE 13G/A

SAB Biotherapeutics, Inc.

SABSNASDAQEQUITYCurrent

Beneficial Ownership Report

Filed Aug 14, 2026Accepted Aug 14, 2026, 6:08 AM EDTCIK 1833214Accession 0001172661-26-003437
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Company context

SAB BIO is a clinical-stage biopharmaceutical company focused on developing multi-specific, high-potency, human immunoglobulin G (hIgG) to treat and prevent immune and autoimmune disorders. Using advanced genetic engineering and antibody science, SAB BIO developed a proprietary technology which holds the potential to generate additional novel therapeutic candidates utilizing the human immune response, without the need for human donors or convalescent plasma. SAB BIO has optimized genetic engineering in the development of transchromosomic cattle, or Tc-Bovine, to produce hIgG. SAB BIO’s drug development production system is able to generate a diverse repertoire of specifically targeted, high-potency, hIgGs that can address a wide range of serious unmet needs in human diseases. The Company’s lead candidate, SAB-142, targets autoimmune T1D with a disease-modifying therapeutic approach that aims to change the T1D treatment paradigm by delaying onset and potentially preventing disease progression of Stage 3 T1D patients. SAB-142 is currently being evaluated in newly diagnosed Stage 3 autoimmune T1D patients in a registrational Phase 2b clinical trial called SAFEGUARD. For more information, visit www.sab.bio.

Current securities

Historical securities (3)

Recent company filings

  1. Other EventsOct 13, 2026
  2. 4 filingSep 18, 2026
  3. 424B3 filingAug 21, 2026
  4. SCHEDULE 13G/A - filed by PERCEPTIVE ADVISORS LLC regarding SAB Biotherapeutics, Inc.Aug 14, 2026
  5. SCHEDULE 13G/A - filed by Caligan Partners LP regarding SAB Biotherapeutics, Inc.Aug 14, 2026

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