Notice of Proposed Sale · 144

Contineum Therapeutics, Inc.

CTNMNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Aug 3, 2026Accepted Aug 3, 2026, 4:19 PM EDTFiling CIK 1861519Accession 0001950047-26-007517

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Structured filing — 144

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer: Contineum Therapeutics, Inc.
Issuer CIK: 0001855175
SEC file number: 001-42001
Phone: 8583335280
Person for whose account securities are to be sold: CARMINE STENGONE
Relationships to issuer: Director · Officer
Street: 3565 General Atomics Court, Suite 200
City: San Diego
State / country code: CA
Postal code: 92121

Securities proposed for sale

Securities proposed for sale · 1 reported row
Security	Proposed units	Aggregate market value	Units outstanding	Approximate sale date	Exchange	Broker / market maker
Common	2,500	38,725.00	32,958,632	08/03/2026	NASDAQ	Morgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name: Morgan Stanley Smith Barney LLC Executive Financial Services
Street: 1 New York Plaza
Street (continued): 8th Floor
City: New York
State / country code: NY
Postal code: 10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
Security	Acquired	Nature of acquisition	Acquired from	Amount acquired	Gift transaction	Payment date	Nature of payment
Common	08/03/2026	Exercise of Stock Options	Issuer	2,500	N	08/03/2026	Cash

Sales reported in the preceding three months

Sales reported in the preceding three months · 2 reported rows
Seller	Security	Sale date	Amount sold	Gross proceeds
10b5-1 Sales for CARMINE STENGONE	Common	07/08/2026	2,500	40,000.00
10b5-1 Sales for CARMINE STENGONE	Common	06/30/2026	10,000	160,080.00

Seller — prior-sale row 1, entry 1

Name: 10b5-1 Sales for CARMINE STENGONE
Street: 3565 General Atomics Court, Suite 200
City: San Diego
State / country code: CA
Postal code: 92121

Seller — prior-sale row 2, entry 1

Name: 10b5-1 Sales for CARMINE STENGONE
Street: 3565 General Atomics Court, Suite 200
City: San Diego
State / country code: CA
Postal code: 92121

Prior-sale reporting

Nothing to report for the preceding three months: N

Notice signature

Notice date: 08/03/2026
Signed: /s/ Carmine Stengone
Plan adoption dates: 09/23/2025

Company context

Contineum Therapeutics (Nasdaq: CTNM) is a clinical-stage biopharmaceutical company pioneering novel, oral small molecule therapies for inflammatory and fibrotic diseases with significant unmet need. PIPE-791, an LPA1 receptor antagonist, is in clinical development for idiopathic pulmonary fibrosis and chronic pain. PIPE-307 is a selective inhibitor of the M1 receptor in clinical development by Johnson & Johnson for major depressive disorder. For more information, please visit www.contineum-tx.com.

Current securities

CTNMNASDAQ · EQUITY · Current

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