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Notice of Proposed Sale · 144

Omeros Corporation

OMERNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Sep 23, 2026Accepted Sep 23, 2026, 4:20 PM EDTFiling CIK 2005787Accession 0001950047-26-009769
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Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
OMEROS CORPORATION
Issuer CIK
0001285819
SEC file number
001-34475
Phone
2066765000
Person for whose account securities are to be sold
DAVID BORGES
Relationships to issuer
Officer
Street
201 Elliott Avenue West
City
SEATTLE
State / country code
WA
Postal code
98119

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Common14,927314,213.3572,388,31609/23/2026NASDAQMorgan Stanley Smith Barney LLC Executive Financial Services

Broker / market maker — proposed row 1, entry 1

Name
Morgan Stanley Smith Barney LLC Executive Financial Services
Street
1 New York Plaza
Street (continued)
8th Floor
City
New York
State / country code
NY
Postal code
10004

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Common09/23/2026Exercise of Stock OptionsIssuer14,927N09/23/2026Cash

Sales reported in the preceding three months

Sales reported in the preceding three months · 4 reported rows
SellerSecuritySale dateAmount soldGross proceeds
10b5-1 Sales for DAVID JOSEPH BORGESCommon09/22/202610,000209,500.00
10b5-1 Sales for DAVID JOSEPH BORGESCommon08/24/202690617,304.60
10b5-1 Sales for DAVID JOSEPH BORGESCommon08/21/202610,000189,500.00
10b5-1 Sales for DAVID JOSEPH BORGESCommon08/13/20265,00084,750.00

Seller — prior-sale row 1, entry 1

Name
10b5-1 Sales for DAVID JOSEPH BORGES
Street
201 Elliott Avenue West
City
SEATTLE
State / country code
WA
Postal code
98119

Seller — prior-sale row 2, entry 1

Name
10b5-1 Sales for DAVID JOSEPH BORGES
Street
201 Elliott Avenue West
City
SEATTLE
State / country code
WA
Postal code
98119

Seller — prior-sale row 3, entry 1

Name
10b5-1 Sales for DAVID JOSEPH BORGES
Street
201 Elliott Avenue West
City
SEATTLE
State / country code
WA
Postal code
98119

Seller — prior-sale row 4, entry 1

Name
10b5-1 Sales for DAVID JOSEPH BORGES
Street
201 Elliott Avenue West
City
SEATTLE
State / country code
WA
Postal code
98119

Prior-sale reporting

Nothing to report for the preceding three months
N

Remarks

The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.

Notice signature

Notice date
09/23/2026
Signed
/s/ David Borges
Plan adoption dates
02/10/2026

Company context

Omeros is an innovative biopharmaceutical company committed to discovering, developing and commercializing first-in-class small-molecule and protein therapeutics for large-market and orphan indications targeting immunologic disorders, including complement-mediated diseases and cancers, as well as addictive and compulsive disorders. Omeros’ lead MASP-2 inhibitor narsoplimab targets the lectin pathway of complement and is the subject of a biologics license application under review by FDA for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy. Omeros’ long-acting MASP-2 inhibitor OMS1029 has successfully completed Phase 1 single- and multiple-ascending dose clinical studies. OMS906, Omeros’ inhibitor of MASP-3, the key activator of the alternative pathway of complement, is in clinical development for treatment of paroxysmal nocturnal hemoglobinuria and complement 3 glomerulopathy. Funded by the National Institute on Drug Abuse, Omeros’ lead phosphodiesterase 7 inhibitor OMS527 is in clinical development for the treatment of cocaine use disorder. Omeros also is advancing a broad portfolio of novel cellular and molecular immuno-oncology programs.

Current securities

Recent company filings

  1. 4 filingAug 28, 2026
  2. 144 filingAug 27, 2026
  3. 144 filingAug 26, 2026
  4. S-8 filingAug 13, 2026
  5. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory ArrangementsAug 13, 2026

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