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BCS

Notice of Proposed Sale · 144

Zenas BioPharma, Inc.

ZBIONASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Aug 19, 2026Accepted Aug 19, 2026, 4:15 PM EDTFiling CIK 2037042Accession 0001968582-26-000858
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Structured filing — 144

primary_doc.xml

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer
ZENAS BIOPHARMA INC
Issuer CIK
0001953926
SEC file number
001-42270
Phone
857-271-2954
Person for whose account securities are to be sold
Zebra Aggregator, LP
Relationships to issuer
Affiliate
Street
852 WINTER STREET, SUITE 250
City
WALTHAM MA
State / country code
MA
Postal code
02451

Securities proposed for sale

Securities proposed for sale · 1 reported row
SecurityProposed unitsAggregate market valueUnits outstandingApproximate sale dateExchangeBroker / market maker
Common1,000,00031,910,00065,176,72308/19/2026NASDAQJ.P. Morgan Securities LLC

Broker / market maker — proposed row 1, entry 1

Name
J.P. Morgan Securities LLC
Street
270 Park Avenue
Street (continued)
10th Floor
City
New York
State / country code
NY
Postal code
10017

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
SecurityAcquiredNature of acquisitionAcquired fromAmount acquiredGift transactionPayment dateNature of payment
Common11/01/2022Series BIssuer1,206,353N11/01/2022Cash

Prior-sale reporting

Nothing to report for the preceding three months
Y

Notice signature

Notice date
08/19/2026
Signed
/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Zebra Aggregator, LP

Company context

Zenas is a clinical-stage global biopharmaceutical company focused on the development and commercialization of therapies for autoimmune diseases and inflammatory conditions. Zenas combines our experienced leadership team with a disciplined global product candidate acquisition approach to identify, acquire and develop product candidates with the potential to deliver clinically meaningful benefits to patients. Zenas is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, Zenas’ lead product candidate, is a bifunctional monoclonal antibody designed to bind CD19 and FcγRIIb to inhibit the activity of B cells implicated in many autoimmune diseases without depleting them. Zenas believes that the unique mechanism of action of obexelimab and its self-administered, subcutaneous injection regimen may enable sustained control across multiple chronic autoimmune diseases. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant, oral, small molecule BTK inhibitor. Orelabrutinib’s mechanism of action targets pathogenic B cells not only in the periphery but also within the CNS. Additionally, it directly modulates macrophages and microglial cells in the CNS, with the potential to address compartmentalized inflammation and disease progression in MS. Zenas’ earlier stage programs include ZB021, a novel, potentially best-in-class, oral, IL-17AA/AF inhibitor, ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant,

Current securities

Recent company filings

  1. Regulation FD DisclosureOct 13, 2026
  2. S-3ASR filingSep 11, 2026
  3. S-8 filingSep 11, 2026
  4. 3 filingSep 2, 2026
  5. 10-Q filingAug 13, 2026

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