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BCS

Current Report · Items 8.01, 9.01 · 8-K

Atrium Therapeutics, Inc.

RNANASDAQEQUITYCurrent

Other Events

Item 8.01 Other Events. On October 27, 2026, Atrium Therapeutics, Inc. (the “Company”) issued a press release announcing that the first patient has been dosed in the Company’s Phase 1/2 Corventis clinical trial evaluating ATR 1072, its lead investigational therapy for the potential treatment of Protein Kinase AMP-activated non-catalytic subunit Gamma 2 (“PRKAG2”) syndrome.…

Filed Oct 27, 2026Accepted Oct 27, 2026, 8:55 AM EDTCIK 2093101Accession 0001193125-26-432949
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Company context

Atrium Therapeutics, Inc. (Nasdaq: RNA) is pioneering targeted delivery of ribonucleic acid (RNA) therapeutics to the heart to transform the standard of care for people living with cardiomyopathies. The Company’s proprietary technology - designed at Avidity Biosciences, Inc. - combines the tissue selectivity of monoclonal antibodies (mAbs) and other targeted delivery ligands with the precision of oligonucleotides and is designed to

Current securities

Recent company filings

  1. Regulation FD Disclosure · Other EventsNov 2, 2026
  2. Other EventsOct 9, 2026
  3. Entry into a Material Definitive Agreement · Unregistered Sales of Equity Securities · Other EventsOct 8, 2026
  4. 4 filingSep 22, 2026
  5. 4 filingSep 22, 2026

Registered securities in this filing

Atrium Therapeutics, Inc. · 8-K · Filed 2026-10-27

As filed in this accession. Current/historical status below comes from the governed listing record; the cover itself remains exact to this filing.

Common stock, par value $0.001 per share

Symbol
RNA
Exchange
NASDAQ
Classification
COMMON
Status
Current
Filing context

Context: duration_2026-10-27_to_2026-10-27

Dimensions: Not supplied

Accession 000119312526432949 · 1 registered-security cover member

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Disclosure sections

Items 8.01, 9.01

Select an item to read the extracted section. The as-filed document remains the primary evidence.

Item 8.01Item 8.01 - Other Events
Item 8.01 Other Events. On October 27, 2026, Atrium Therapeutics, Inc. (the “Company”) issued a press release announcing that the first patient has been dosed in the Company’s Phase 1/2 Corventis clinical trial evaluating ATR 1072, its lead investigational therapy for the potential treatment of Protein Kinase AMP-activated non-catalytic subunit Gamma 2 (“PRKAG2”) syndrome. A copy of this press release is attached to this Current Report on Form 8-K as Exhibit 99.1 and is incorporated herein by reference.
Filed exhibits (1)
EX-99.1 (by filename) d134020dex991.htm

Exhibit 99.1 Atrium Therapeutics Doses First Patient in Corventis™, the First Interventional Clinical Trial for People Living with PRKAG2 Syndrome - Global Phase 1/2 trial will evaluate ATR 1072 in approximately 37 participants - - Initial proof of concept data expected in second half of 2027 - SAN DIEGO, Oct. 27, 2026 - Atrium Therapeutics, Inc. (Nasdaq: RNA) (the “Company”), a biopharmaceutical company advancing precision cardiology by developing RNA therapeutics targeted to the heart, today announced that the first patient has been dosed in the Phase 1/2 Corventis clinical trial evaluating ATR 1072, its lead investigational therapy for the potential treatment of PRKAG2 (Protein Kinase AMP-activated non-catalytic subunit Gamma 2) syndrome. The Company expects to report initial proof-of-concept data from Corventis in the second half of 2027. “Dosing the first patient in the Corventis clinical trial is a milestone for Atrium and, more importantly, for the PRKAG2 community. This is the first clinical trial for people living with PRKAG2 syndrome evaluating a potential treatment for the underlying cause of the disease. It is also an important step for the broader genetic cardiomy…

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