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BCS

Changes in Beneficial Ownership · 4

Braveheart Bio, Inc.

BRVENASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Aug 11, 2026Accepted Aug 11, 2026, 5:53 PM EDTFiling CIK 2131524Accession 0001231919-26-000859
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Structured filing — 4

form4-08112026_090855.xml

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Filing details

Report period
2026-08-07
Issuer
Braveheart Bio, Inc.
Issuer CIK
0002131524
Trading symbol
BRVE

Reporting owner 1

Name
AH Bio Fund IV, L.P.
Reporting owner CIK
0001889476
Relationship
10% owner
Address
C/O ANDREESSEN HOROWITZ, 2865 SAND HILL ROAD, SUITE 101, MENLO PARK, CA, 94025

Reporting owner 2

Name
AH Equity Partners Bio IV, L.L.C.
Reporting owner CIK
0001889898
Relationship
10% owner
Address
C/O ANDREESSEN HOROWITZ, 2865 SAND HILL ROAD, SUITE 101, MENLO PARK, CA, 94025

Reporting owner 3

Name
Andreessen Marc L
Reporting owner CIK
0001160077
Relationship
10% owner
Address
C/O ANDREESSEN HOROWITZ, 2865 SAND HILL ROAD, SUITE 101, MENLO PARK, CA, 94025

Reporting owner 4

Name
HOROWITZ BENJAMIN A
Reporting owner CIK
0001166586
Relationship
10% owner
Address
C/O ANDREESSEN HOROWITZ, 2865 SAND HILL ROAD, SUITE 101, MENLO PARK, CA, 94025

Non-derivative transactions

Non-derivative transactions · 2 reported rows
SecurityTransaction dateCodeAmountA / DPrice (USD)Owned afterOwnershipNature of ownership
Common Stock2026-08-07C · Form 49,132,420A[F1]9,132,420IBy AH Bio Fund IV, L.P.[F2][F3]
Common Stock2026-08-07P · Form 41,100,000A1810,232,420IBy AH Bio Fund IV, L.P.[F2][F3]
Table key
C · Form 4
Derivative conversion
A
Acquired
I
Indirect
P · Form 4
Purchase on the market or privately

Derivative transactions

Derivative transactions · 1 reported row
SecurityConversion / exercise price (USD)Transaction dateCodeAmountA / DPrice (USD)ExercisableExpiresUnderlying securityUnderlying sharesOwned afterOwnershipNature of ownership
Series A Preferred Stock[F1]2026-08-07C · Form 440,000,000D0[F1][F1]Common Stock9,132,4200IBy AH Bio Fund IV, L.P.[F2][F3]
Table key
C · Form 4
Derivative conversion
D
Disposed
I
Indirect

Footnotes

F1
Series A Preferred Stock automatically converted into Common Stock immediately prior to the closing of the Issuer's initial public offering for no additional consideration, on a 4.38-for-1 basis. The Series A Preferred Stock had no expiration date.↩ 1↩ 2↩ 3↩ 4
F2
The reported securities are held by AH Bio Fund IV, L.P. ("AH Bio Fund IV"), for itself and as nominee for AH Bio Fund IV-B, L.P., AH 2022 Annual Fund, L.P., AH 2022 Annual Fund-B, L.P., AH 2022 Annual Fund-QC, L.P. and CLF Partners III, LP. AH Equity Partners Bio IV, L.L.C. ("AH EP Bio IV") is the general partner of AH Bio Fund IV and has sole voting and dispositive power with regard to the securities held by AH Bio Fund IV for itself and as nominee. The managing members of AH EP Bio IV are Marc Andreessen and Ben Horowitz. Marc Andreessen and Ben Horowitz may be deemed to share voting and dispositive power with respect to the securities held by AH Bio Fund IV for itself and as nominee.↩ 1↩ 2↩ 3
F3
(Continued from Footnote 2) Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of the securities held by AH Bio Fund IV for itself and as nominee (and this report shall not be deemed an admission that any such person is the beneficial owner of such securities), except to the extent of such person's pecuniary interest therein, if any.↩ 1↩ 2↩ 3

Signature 1

Signed
AH Bio Fund IV, L.P., By AH Equity Partners Bio IV, L.L.C., Its General Partner, By /s/ Phil Hathaway, Chief Operating Officer
Date
2026-08-11

Signature 2

Signed
AH Equity Partners Bio IV, L.L.C., By /s/ Phil Hathaway, Chief Operating Officer
Date
2026-08-11

Signature 3

Signed
/s/ Phil Hathaway, Attorney-in-Fact for Marc L. Andreessen
Date
2026-08-11

Signature 4

Signed
/s/ Phil Hathaway, Attorney-in-Fact for Benjamin Horowitz
Date
2026-08-11

Company context

We are a clinical‑stage biopharmaceutical company focused on developing therapies for patients with hypertrophic cardiomyopathy (“HCM”) and other serious cardiovascular diseases. Our lead product candidate, BHB‑1893, is a next-generation oral small‑molecule cardiac myosin inhibitor (“CMI”), that we are developing for the treatment of obstructive HCM (“oHCM”) and non‑obstructive HCM (“nHCM”). Our goal is to improve the treatment options for these patients by enhancing speed of onset, depth of gradient response, systolic safety, and reversibility, and reducing prescribing complexity. BHB-1893 was initially discovered and developed by Jiangsu Hengrui Pharmaceuticals Co., Ltd. (“Hengrui”) in China. We in-licensed BHB-1893 pursuant to an exclusive license agreement with Hengrui (the “Exclusive License Agreement”), and as such, all clinical trials of BHB-1893 completed to date were designed, sponsored, and conducted by Hengrui, primarily in China, with one Phase 1 trial conducted in Australia. We were not involved in the design, conduct, or oversight of these trials.

Current securities

Recent company filings

  1. 10-Q filingSep 8, 2026
  2. Results of Operations and Financial ConditionSep 8, 2026
  3. 3 filingAug 14, 2026
  4. 4 filingAug 11, 2026
  5. 4 filingAug 11, 2026

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