Notice of Proposed Sale · 144

Repligen Corporation

RGENNASDAQEQUITYCurrent

Notice of Proposed Sale

Filed Jul 16, 2026Accepted Jul 16, 2026, 1:45 PM EDTFiling CIK 730272Accession 0001959173-26-005250

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Structured filing — 144

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Notice of proposed sale. The proposed amounts below do not establish that a sale occurred.

Proposed-sale notice

Issuer: REPLIGEN CORP
Issuer CIK: 0000730272
SEC file number: 000-14656
Phone: 7814499560
Person for whose account securities are to be sold: Garland Jason K
Relationships to issuer: Officer
Street: 41 SEYON STREET
Street (continued): BUILDING 1, SUITE 100
City: WALTHAM
State / country code: MA
Postal code: 02453

Securities proposed for sale

Securities proposed for sale · 1 reported row
Security	Proposed units	Aggregate market value	Units outstanding	Approximate sale date	Exchange	Broker / market maker
Common	530	79,500.00	56,407,740	07/16/2026	NASDAQ	Fidelity Brokerage Services LLC

Broker / market maker — proposed row 1, entry 1

Name: Fidelity Brokerage Services LLC
Street: 900 Salem Street
City: Smithfield
State / country code: RI
Postal code: 02917

Acquisition of securities to be sold

Acquisition of securities to be sold · 1 reported row
Security	Acquired	Nature of acquisition	Acquired from	Amount acquired	Gift transaction	Payment date	Nature of payment
Common	02/27/2025	Restricted Stock Vesting	Issuer	530	N	02/27/2025	Compensation

Sales reported in the preceding three months

Sales reported in the preceding three months · 1 reported row
Seller	Security	Sale date	Amount sold	Gross proceeds
Jason K. Garland	Common	06/25/2026	733	106,285.00

Seller — prior-sale row 1, entry 1

Name: Jason K. Garland
Street: 41 Seyon Street
Street (continued): Bldg. 1, Suite 100
City: Waltham
State / country code: MA
Postal code: 02453

Prior-sale reporting

Nothing to report for the preceding three months: N

Notice signature

Notice date: 07/16/2026
Signed: /s/Wade Moss, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Jason K. Garland
Plan adoption dates: 12/08/2025

Company context

Repligen Corporation is a global life sciences company that develops and commercializes highly innovative bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs. We are “inspiring advances in bioprocessing” for the customers we serve, primarily biopharmaceutical drug developers and contract development and manufacturing organizations (CDMOs) worldwide. Our focus areas are Filtration and Fluid Management, Chromatography, Process Analytics and Proteins. Our corporate headquarters are located in Waltham, Massachusetts, and the majority of our manufacturing sites are in the U.S., with additional key sites in Estonia, Germany, Ireland, the Netherlands and Sweden. For more information about the company see our website at www.repligen.com, and follow us on LinkedIn.

Current securities

RGENNASDAQ · EQUITY · Current

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