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Security

Apnimed, Inc. Common Stock · APMD

APMDNASDAQCommon stockCurrentCIK 1745648Updated Nov 6, 2026

Company: Apnimed, Inc. →

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About the company

We are a late stage clinical pharmaceutical company dedicated to the discovery, development and commercialization of novel oral therapies that address the neurobiology of sleep-related breathing diseases. Our sole clinical product candidate, AD109 (Oxnimbi), is an investigational, fixed-dose, anti-apneic neuromuscular modulator, combining a novel anti-muscarinic and a selective norepinephrine reuptake inhibitor (NRI) for the treatment of obstructive sleep apnea (OSA). Oxnimbi is designed to target the neuromuscular defect of OSA by improving upper airway muscle activity to help maintain airway patency and prevent airway collapse during sleep. Based on results from two registrational trials, we submitted a New Drug Application (NDA) for Oxnimbi to the U.S. Food and Drug Administration (FDA) in April 2026, which was accepted for review by the FDA in July 2026. The registrational trials were Phase 3, randomized, double-blind, placebo-controlled, parallel-arm trials in adults with mild to severe OSA, LunAIRo and SynAIRgy, which together enrolled approximately 1,300 patients and represent one of the largest and most diverse cohorts ever studied in an OSA pharmacologic trial. LunAIRo was…

424B4 · 2026-07-31 · 0001193125-26-328422

Company description from the cited filing.

Offerings

Registration 333-297377

424B4 · 2026-07-31 · 0001193125-26-328422

Terms from the governing filing for this registration; not a claim that the offering is open today.

Gross proceeds
192000000.0
Net proceeds
178560000.0
Deal price
16.0
Shares
12000000
Offering price
$16.00
Ticker
APMD

Underwriters: BofA Securities, Inc., Evercore Group L.L.C.

Registration 333-297849

S-1MEF · 2026-07-30 · 0001193125-26-326515

Terms from the governing filing for this registration; not a claim that the offering is open today.

Filing attachments

apmd-ex99_1.htm · S-8 · 2026-09-08

APNIMED, INC. 2026 INDUCEMENT PLAN SECTION 1. GENERAL PURPOSE OF THE PLAN; DEFINITIONS The name of the plan is the Apnimed, Inc. 2026 Inducement Plan (as amended from time to time, the “Plan”). The purpose of the Plan is to enable Apnimed, Inc. (the “Company”) and its Affiliates to induce highly-qualified prospective officers and employees who are Eligible Employees to accept employment and to provide them with a proprietary interest in the Company. It is anticipated that providing such pers…

S-8 · 2026-09-08 · 0001193125-26-385357

Read attachment ↗
apmd-ex99_2.htm · S-8 · 2026-09-08

NON-QUALIFIED STOCK OPTION AGREEMENT UNDER THE APNIMED, INC. 2026 INDUCEMENT PLAN Name of Optionee: No. of Option Shares: Option Exercise Price per Share: $ Grant Date: Expiration Date: Pursuant to the Apnimed, Inc. 2026 Inducement Plan as amended through the date hereof (the “Plan”), Apnimed, Inc. (the “Company”) hereby grants to the Optionee named above an option (the “Stock Option”) to purchase on or prior to the Expiration Date specified above all or part of the number of shares of Co…

S-8 · 2026-09-08 · 0001193125-26-385357

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apmd-ex99_1.htm · 8-K · 2026-09-08

EX-99.1 2 apmd-ex99_1.htm EX-99.1 EX-99.1 EX-99.1 Apnimed Reports Second Quarter 2026 Financial Results and Provides Corporate Update • U.S. Food and Drug Administration (“FDA”) Accepted the NDA for AD109, with a proposed proprietary name Oxnimbi™, and assigned a PDUFA target action date of February 28, 2027 • If approved, Oxnimbi has the potential to become the first oral pharmacologic therapy designed to address the neuromuscular root cause of upper airway collapse for the millions of …

8-K · 2026-09-08 · 0001193125-26-385355

Read attachment ↗
apni-ex4_1.htm · S-1/A · 2026-07-27

Exhibit 4.1 The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written out in full according to applicable laws or regulations: TEN COM as tenants in common UNIF GIFT MIN ACT –– ..................Custodian .................. TEN ENT as te…

S-1/A · 2026-07-27 · 0001193125-26-316811

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apni-ex4_2.htm · S-1 · 2026-07-10

Exhibit 4.2 NEITHER THIS SECURITY NOR THE SECURITIES INTO WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR ANY STATE SECURITIES OR “BLUE SKY LAWS,” AND MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APP…

S-1 · 2026-07-10 · 0001193125-26-300909

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apni-ex4_3.htm · S-1 · 2026-07-10

Exhibit 4.3 APNIMED, INC. SIXTH AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT TABLE OF CONTENTS Page 1. Definitions 1 2. Registration Rights 4 2.1 Demand Registration …

S-1 · 2026-07-10 · 0001193125-26-300909

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