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BCS

Beneficial Ownership Report · SCHEDULE 13G/A

uniQure N.V.

QURENASDAQEQUITYCurrent

Beneficial Ownership Report

Filed Oct 16, 2026Accepted Oct 16, 2026, 2:01 PM EDTFiling CIK 1590560Accession 0000019617-26-000387
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Structured filing — SCHEDULE 13G/A

primary_doc.xml

Open full document ↗

Amendment · This filing reports the amendment as submitted.

Subject company

Company
uniQure N.V.
Company CIK
0001590560
Street
Paasheuvelweg 25a
Street (continued)
1105 BP Amsterdam
City
The Netherlands
State / country code
XX
Postal code
00000

Statement details

Amendment number
1
Security class
Ordinary Shares, par value 0.05
Event date
09/30/2026
Rule designation
Rule 13d-1(b)

Reporting person 1

Name
JPMORGAN CHASE & CO.
Citizenship / organization
DE
Reporting person type
HC
Aggregate amount owned
5,951,794.0
Percent of class
8.5
Sole voting power
5,654,307.0
Shared voting power
1.0
Sole dispositive power
5,943,150.0
Shared dispositive power
1.0

Item 1

Issuer

uniQure N.V.

Principal executive office address

Paasheuvelweg 25a 1105 BP Amsterdam The Netherlands

Item 2

Citizenship

DE

Filing person

JPMORGAN CHASE & CO.

Principal business or residence address

270 Park Avenue,,New York, NY 10017

Item 3

Not applicable indication

N

Type of filing person

HC

Item 4

Percent of class

8.5

Amount beneficially owned

5951794

Sole voting power

5654307

Shared voting power

1

Sole dispositive power

5943150

Shared dispositive power

1

Item 5

Not applicable indication

Y

Ownership of 5% or less

N

Item 6

Not applicable indication

N

Ownership on behalf of another person

Not Applicable

Item 7

Not applicable indication

N

Subsidiaries

JPMorgan Asset Management (UK) Limited; JPMorgan Chase Bank, National Association; J.P. Morgan Investment Management Inc.; J.P. Morgan Wealth Management Solutions Inc.

Item 8

Not applicable indication

N

Group members

Not Applicable

Item 9

Not applicable indication

N

Item 10

Not applicable indication

N

Certifications

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

Signature 1

Reporting person
JPMORGAN CHASE & CO.
Signed
Rachel Tsvaygoft
Title
Vice President
Date
10/16/2026

Company context

uniQure is delivering on the promise of gene therapy - single treatments with potentially curative results. The approvals of uniQure’s gene therapy for hemophilia B - an historic achievement based on more than a decade of research and clinical development - represent a major milestone in the field of genomic medicine and ushers in a new treatment approach for patients living with hemophilia. uniQure is now advancing a pipeline of proprietary gene therapies for the treatment of patients with Huntington's disease, refractory temporal lobe epilepsy, Fabry disease, and other severe diseases. www.uniQure.com

Current securities

Recent company filings

  1. Regulation FD DisclosureSep 29, 2026
  2. Regulation FD DisclosureSep 2, 2026
  3. Results of Operations and Financial ConditionJul 29, 2026
  4. S-8 filingJul 29, 2026
  5. 10-Q filingJul 29, 2026

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