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BCS

Changes in Beneficial Ownership · 4

Tempus AI, Inc.

TEMNASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Oct 29, 2026Accepted Oct 29, 2026, 4:15 PM EDTFiling CIK 1717115Accession 0001114357-26-000042
Share

Structured filing — 4

form4-10292026_041001.xml

Open full document ↗

Filing details

Report period
2026-10-27
Issuer
Tempus AI, Inc.
Issuer CIK
0001717115
Trading symbol
TEM
Rule 10b5-1 indication
Checked

Reporting owner 1

Name
LEFKOFSKY ERIC P
Reporting owner CIK
0001114357
Relationship
Director · Officer · 10% owner
Officer title
CEO and Chairman
Address
C/O TEMPUS AI, INC., 600 WEST CHICAGO AVENUE, SUITE 510, CHICAGO, IL, 60654

Non-derivative transactions

Non-derivative transactions · 24 reported rows
SecurityTransaction dateCodeAmountA / DPrice (USD)Owned afterOwnershipNature of ownership
Class A Common Stock2026-10-27S · Form 4[F1]10,428D67.36[F2]8,534,855IBy Gray Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]7,592D68[F4]8,527,263IBy Gray Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]1,495D69.28[F5]8,525,768IBy Gray Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]6,312D70.58[F6]8,519,456IBy Gray Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]16,414D71.56[F7]8,503,042IBy Gray Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]15,259D72.31[F8]8,487,783IBy Gray Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]24,597D67.36[F2]14,825,872IBy Blue Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]17,825D68[F4]14,808,047IBy Blue Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]3,510D69.28[F5]14,804,537IBy Blue Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]14,820D70.58[F6]14,789,717IBy Blue Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]38,489D71.56[F7]14,751,228IBy Blue Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]35,759D72.31[F8]14,715,469IBy Blue Media, LLC[F3]
Class A Common Stock2026-10-27S · Form 4[F1]1,282D67.36[F2]800,849IBy Lefkofsky Family Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]961D68[F4]799,888IBy Lefkofsky Family Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]195D69.28[F5]799,693IBy Lefkofsky Family Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]824D70.58[F6]798,869IBy Lefkofsky Family Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]2,167D71.56[F7]796,702IBy Lefkofsky Family Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]2,071D72.31[F8]794,631IBy Lefkofsky Family Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]9,132D67.36[F2]90,868IBy Vas.org Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]6,636D68[F4]84,232IBy Vas.org Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]1,300D69.28[F5]82,932IBy Vas.org Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]5,486D70.58[F6]77,446IBy Vas.org Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]14,237D71.56[F7]63,209IBy Vas.org Foundation[F3]
Class A Common Stock2026-10-27S · Form 4[F1]13,209D72.31[F8]50,000IBy Vas.org Foundation[F3]
Table key
S · Form 4
Sale on the market or privately
D
Disposed
I
Indirect

Non-derivative holdings

Non-derivative holdings · 5 reported rows
SecurityAmount ownedOwnershipNature of ownership
Class A Common Stock2,098,130D
Class A Common Stock406IBy 346 Long LLC[F3]
Class A Common Stock5,715,203IBy Lefkofsky Family 2025 GRAT[F3]
Class A Common Stock206IBy Black Media, LLC[F3]
Class A Common Stock4,284,797IBy Lefkofsky Family 2026 GRAT[F3]
Table key
D
Direct
I
Indirect

Footnotes

F1
This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 8, 2026.↩ 1↩ 2↩ 3↩ 4↩ 5↩ 6↩ 7↩ 8↩ 9↩ 10↩ 11↩ 12↩ 13↩ 14↩ 15↩ 16↩ 17↩ 18↩ 19↩ 20↩ 21↩ 22↩ 23↩ 24
F2
The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $66.69 to $67.6836 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1↩ 2↩ 3↩ 4
F3
The Reporting Person is (i) a member of, and controls a limited liability company that is a member of, 346 Long LLC, (ii) the sole manager of each of Black Media, LLC, Blue Media, LLC and Gray Media, LLC, (iii) a trustee of each of Lefkofsky Family Foundation and Vas.org Foundation. The Reporting Person's spouse is the trustee of the Lefkofsky Family 2025 GRAT and Lefkofsky Family 2026 GRAT.↩ 1↩ 2↩ 3↩ 4↩ 5↩ 6↩ 7↩ 8↩ 9↩ 10↩ 11↩ 12↩ 13↩ 14↩ 15↩ 16↩ 17↩ 18↩ 19↩ 20↩ 21↩ 22↩ 23↩ 24↩ 25↩ 26↩ 27↩ 28
F4
The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.69 to $68.68 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1↩ 2↩ 3↩ 4
F5
The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $68.75 to $69.74 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1↩ 2↩ 3↩ 4
F6
The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.05 to $71.04 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1↩ 2↩ 3↩ 4
F7
The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $71.045 to $72.0442 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1↩ 2↩ 3↩ 4
F8
The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $72.045 to $72.84 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.↩ 1↩ 2↩ 3↩ 4

Signature 1

Signed
/s/ Andrew Polovin, Attorney-in-Fact
Date
2026-10-29

Company context

Tempus is a technology company making precision medicine a reality through the practical application of artificial intelligence in healthcare. With one of the world’s largest libraries of de-identified multimodal data and an intelligent operating system that makes that data accessible and actionable, Tempus connects AI, diagnostics and clinical workflows to deliver more personalized patient care and accelerate the discovery, development and delivery of better medicines. By continuously transforming data into insights, Tempus

Current securities

Recent company filings

  1. SCHEDULE 13G/A - filed by ARK Investment Management LLC regarding Tempus AI, Inc.Nov 6, 2026
  2. 4 filingNov 4, 2026
  3. 10-Q filingNov 2, 2026
  4. Results of Operations and Financial Condition · Regulation FD DisclosureNov 2, 2026
  5. SCHEDULE 13G/A - filed by KEYWELL BRADLEY A regarding Tempus AI, Inc.Oct 28, 2026

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