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BCS

Changes in Beneficial Ownership · 4

Scholar Rock Holding Corporation

SRRKNASDAQEQUITYCurrent

Changes in Beneficial Ownership

Filed Oct 27, 2026Accepted Oct 27, 2026, 7:47 PM EDTFiling CIK 1727196Accession 0001253170-26-000014
Share

Structured filing — 4

form4-10272026_111033.xml

Open full document ↗

Filing details

Report period
2026-10-23
Issuer
Scholar Rock Holding Corp
Issuer CIK
0001727196
Trading symbol
SRRK

Reporting owner 1

Name
AKKARAJU SRINIVAS
Reporting owner CIK
0001253170
Relationship
Director
Address
628 MIDDLEFIELD ROAD, PALO ALTO, CA, 94301

Non-derivative transactions

Non-derivative transactions · 6 reported rows
SecurityTransaction dateCodeAmountA / DPrice (USD)Owned afterOwnershipNature of ownership
Common Stock2026-10-23P · Form 447,000A41.31[F1]6,331,029[F2]IBy Samsara BioCapital, L.P.[F3]
Common Stock2026-10-23P · Form 494,000A41.31[F1]624,038IBy Samsara Opportunity Fund, L.P.[F4]
Common Stock2026-10-23P · Form 4500A41.82[F5]6,331,529IBy Samsara BioCapital, L.P.[F3]
Common Stock2026-10-23P · Form 41,000A41.82[F5]625,038IBy Samsara Opportunity Fund, L.P.[F4]
Common Stock2026-10-26P · Form 448,988A41.59[F6]6,380,517IBy Samsara BioCapital, L.P.[F3]
Common Stock2026-10-26P · Form 497,982A41.59[F6]723,020IBy Samsara Opportunity Fund, L.P.[F4]
Table key
P · Form 4
Purchase on the market or privately
A
Acquired
I
Indirect

Non-derivative holdings

Non-derivative holdings · 1 reported row
SecurityAmount ownedOwnership
Common Stock27,971D
Table key
D
Direct

Footnotes

F1
The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $40.77 to $41.75 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote.↩ 1↩ 2
F2
The shares held by Samsara BioCapital LP ("Samsara LP") prior to the reported transaction reflect the disposition of 83,585 shares in which the Reporting Person had no pecuniary interest. The disposition of such shares by Samsara LP did not involve a change in the Reporting Person's beneficial ownership of such shares and, accordingly, was exempt from reporting under Section 16.↩ 1
F3
Securities are directly held by Samsara LP. Samsara BioCapital GP, LLC ("Samsara LLC") is the general partner of Samsara LP and may be deemed to beneficially own the securities held by Samsara LP. The Reporting Person has voting and investment power over the securities held by Samsara LP and, accordingly, may be deemed to beneficially own the securities held by Samsara LP. The Reporting Person disclaims beneficial ownership in these securities except to the extent of his pecuniary interest therein.↩ 1↩ 2↩ 3
F4
Securities are directly held by Samsara Opportunity Fund, L.P. ("Samsara Opportunity Fund"). Samsara Opportunity Fund GP, LLC ("Samsara Opportunity GP") is the general partner of Samsara Opportunity Fund and may be deemed to beneficially own the securities held by Samsara Opportunity Fund. The Reporting Person has voting and investment power over the securities held by Samsara Opportunity Fund and, accordingly, may be deemed to beneficially own the securities held by Samsara Opportunity Fund. The Reporting Person disclaims beneficial ownership in these securities except to the extent of his pecuniary interest therein.↩ 1↩ 2↩ 3
F5
The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $41.78 to $41.85 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote.↩ 1↩ 2
F6
The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $41.15 to $41.93 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote.↩ 1↩ 2

Signature 1

Signed
/s/ Srinivas Akkaraju
Date
2026-10-27

Company context

Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need. Scholar Rock intends to commercialize ISEMBYLD (apitegromab-mstn) globally, beginning in the U.S. for individuals living with SMA who are 2 years of age and older and currently receiving a survival motor neuron 2 (SMN2)-targeted treatment.

Current securities

Recent company filings

  1. 4 filingSep 23, 2026
  2. Regulation FD DisclosureSep 15, 2026
  3. Regulation FD Disclosure · Other EventsSep 14, 2026
  4. SCHEDULE 13G/A - filed by Redmile Group, LLC regarding Scholar Rock Holding CorpAug 14, 2026
  5. Other EventsAug 6, 2026

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